Intravenous Immunoglobulin (IVIg) for unexplained infertility: a case series

被引：0
|
作者：
Genest, G. [1 ]
Elliott, B. [2 ]
Spitzer, K. [3 ]
Laskin, C. A. [4 ]
Buckett, W. [5 ]
Lapensee, L. [6 ,7 ]
Kadoch, I. J. [6 ,7 ]
Gold, P. [1 ]
机构：
[1] McGill Univ, Montreal Gen Hosp, Dept Immunol, Montreal, PQ, Canada
[2] McGill Univ, Montreal, PQ, Canada
[3] Trio Fertil, Toronto, ON, Canada
[4] Univ Toronto, Dept Med & Obstet, Toronto, ON, Canada
[5] McGill Univ, Reprod Ctr, Montreal, PQ, Canada
[6] Univ Montreal, Dept Obstet & Gynecol, Montreal, PQ, Canada
[7] Ovo Clin, Dept Reprod Med, Montreal, PQ, Canada
来源：
CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY | 2018年 / 45卷 / 05期
关键词：
Immunology; Infertility; Maternal-fetal medicine; PREGNANCY;
D O I：
10.12891/ceog4566.2018
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Intravenous Immunoglobulin (IVIg) is a potential treatment for immune mediated reproductive failure (IMRF), but its role in infertility treatments remains controversial. There is evidence that administering IVIg before conception improves pregnancy outcomes. In the present cohort, 13/15 (86%) patients had a live birth after receiving pre-conceptual Wig at immunomodulatory doses. No serious maternal or fetal side effects directly attributable to IVIg were reported. The present results support the need for a randomized controlled trial (RCT) with this protocol.
引用
收藏
页码：699 / 701
页数：3
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