Organic-Soluble Chitosan/Polyhydroxybutyrate Ultrafine Fibers as Skin Regeneration Prepared by Electrospinning

被引:30
|
作者
Ma, Guiping [1 ,2 ]
Yang, Dongzhi [1 ,2 ]
Wang, Kemin [1 ,2 ]
Han, Jing [1 ,2 ]
Ding, Shumin [3 ]
Song, Guoqiang [3 ]
Nie, Jun [1 ,2 ]
机构
[1] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
[2] Beijing Univ Chem Technol, Key Lab Beijing, Beijing 100029, Peoples R China
[3] Jiangsu Polytech Univ, Dept Chem Engn, Changzhou 213164, Jiangsu, Peoples R China
关键词
biomaterials; thermogravimetric analysis (TGA); biological applications of polymers; QUATERNIZED CHITOSAN; POLY; 3-HYDROXYBUTYRATE; SILK FIBROIN; NANOFIBERS; SURFACE; FABRICATION; MORPHOLOGY; SCAFFOLDS; CHITIN; MATS;
D O I
10.1002/app.32671
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
In the present contribution, the ultrafine fiber membranes of polyhydroxybutyrate (PHB) and organic-soluble chitosan(O-CS) was prepared by electrospinning. The structure and thermal stability were studied by infrared (FTIR) and thermogravimetric analysis (TG). The surface properties of ultrafine fibers were estimated by contact angle measurements using water. The morphology was observed by scanning electron microscopy (SEM). The cytotoxicity assessment with mouse fibroblast cells (L929) was also investigated. Cell culture results showed that it benefits promoting the cell attachment and proliferation. The results showed it could be as tissue engineering for skin regeneration. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 118: 3619-3624,2010
引用
收藏
页码:3619 / 3624
页数:6
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