Multiple and Recurrent Squamous Cell Carcinoma of the Oral Cavity After Graft-Versus-Host Disease

被引：10
|
作者：
Weng, Xiuhong [1 ]
Xing, Yuzhen [1 ]
Cheng, Bo [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Dept Stomatol, Wuhan Union Hosp, Tongji Med Coll, 1277 Jiefang Ave, Wuhan 430022, Hubei, Peoples R China
来源：
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2017年 / 75卷 / 09期
基金：
中国国家自然科学基金;
关键词：
TRADITIONAL CHINESE MEDICINE; LONG-TERM SURVIVORS; FANCONI-ANEMIA; SOLID CANCERS; TRANSPLANTATION; THERAPY; HEAD; DYSPLASIA;
D O I：
10.1016/j.joms.2017.02.012
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Oral squamous cell carcinoma (OSCC) is one of the most common secondary solid tumors in patients who have undergone hematopoietic stem cell transplantation (HSCT). However, according to previous reports, multiple and recurrent OSCC is very rare. The presented case shows the susceptibility to the development of secondary malignancies, particularly oral cancer, of patients who present with chronic graft-versus-host disease after HSCT. OSCC after HSCT appears to be more invasive and has a tendency to recur, with a poor prognosis. Therefore, regular and thorough evaluations of the oral mucosa are recommended for all patients who undergo bone marrow transplantation and have chronic graft-versus-host disease. (C) 2017 American Association of Oral and Maxillofacial Surgeons
引用
收藏
页码：1899 / 1905
页数：7
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