Alcohol addiction is associated with decreased limbic mGluR5 availability: a 18F-FPEB PET study in human.

被引：0
|
作者：
Leurquin-Sterk, Gil [4 ]
Crunelle, Cleo [5 ]
Ceccarini, Jenny [4 ]
de Laat, Bart [2 ]
Peuskens, Hendrik [3 ]
Bormans, Guy [1 ]
Van Laere, Koen [4 ]
机构：
[1] Univ Leuven, KU Leuven, Lab Radiopharm, Leuven, Belgium
[2] Univ Leuven, KU Leuven, Mol Small Anim Imaging Ctr, MoSAIC, Leuven, Belgium
[3] Univ Leuven, KU Leuven, UPC KU Leuven, Univ Psychiat Ctr, Leuven, Belgium
[4] Univ Hosp Gasthuisberg, Nucl Med, Leuven, Belgium
[5] Univ Antwerp, Toxicol Ctr, Antwerp, Belgium
来源：
JOURNAL OF NUCLEAR MEDICINE | 2016年 / 57卷
关键词：
D O I：
暂无
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
15
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Dibenzothiophene sulfonium salts as leaving groups for aromatic [18F]fluorination - exemplified by highly efficient direct labeling of the mGluR5 PET tracer [18F]FPEB
    Gendron, Thibault
    Sander, Kerstin
    Cybulska, Klaudia
    Gray, Vincent
    Arstad, Erik
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2015, 58 : S8 - S8
  • [32] EVALUATION AND QUANTIFICATION OF 18F-FPEB AS RADIOLIGAND FOR PET IMAGING OF THE METABOTROPIC GLUTAMATE RECEPTOR 5 IN RAT BRAIN.
    de Laat, B.
    Koole, M.
    Celen, S.
    Leurquin-Sterk, G.
    Bormans, G.
    Van Laere, K.
    Casteels, C.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2016, 36 : 612 - 613
  • [33] Potential utility of 11C-FPEB as a PET ligand for imaging metabotropic glutamate receptor 5 (mGluR5) in human brain
    Lohith, Talakad
    Fabrice, Simeon
    Zoghbi, Sami
    Morse, Cheryl
    Pike, Victor
    Innis, Robert
    Fujita, Masahiro
    JOURNAL OF NUCLEAR MEDICINE, 2014, 55
  • [34] Preparation of the metabotropic glutamate receptor 5 (mGluR5) PET tracer [18F]FPEB for human use: An automated radiosynthesis and a novel one-pot synthesis of its radiolabeling precursor
    Lim, Keunpoong
    Labaree, David
    Li, Songye
    Huang, Yiyun
    APPLIED RADIATION AND ISOTOPES, 2014, 94 : 349 - 354
  • [35] Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB
    Liang, Steven H.
    Wang, Lu
    Stephenson, Nickeisha A.
    Rotstein, Benjamin H.
    Vasdev, Neil
    NATURE PROTOCOLS, 2019, 14 (05) : 1530 - 1545
  • [36] Effects of alcohol exposure on the glutamatergic system: a combined longitudinal 18F-FPEB and 1H-MRS study in rats
    de Laat, Bart
    Weerasekera, Akila
    Leurquin-Sterk, Gil
    Gsell, Willy
    Bormans, Guy
    Himmelreich, Uwe
    Casteels, Cindy
    Van Laere, Koen
    ADDICTION BIOLOGY, 2019, 24 (04) : 696 - 706
  • [37] Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB
    Steven H. Liang
    Lu Wang
    Nickeisha A. Stephenson
    Benjamin H. Rotstein
    Neil Vasdev
    Nature Protocols, 2019, 14 : 1530 - 1545
  • [38] Limbic system mGluR5 availability in cocaine dependent subjects: A high-resolution PET [11C]ABP688 study
    Milella, M. S.
    Marengo, L.
    Larcher, K.
    Fotros, A.
    Dagher, A.
    Rosa-Neto, P.
    Benkelfat, C.
    Leyton, M.
    NEUROIMAGE, 2014, 98 : 195 - 202
  • [39] Preparation of the metabotropic glutamate receptor 5 (mGluR5) tracer [18F]-FPEB for human use: An automated radiosynthesis and a novel one-pot synthesis of the radiolabeling precursor
    Lim, Keunpoong
    Huang Yiyun
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2013, 56 : S150 - S150
  • [40] Lower Limbic System mGluR5 Availability in Cocaine Dependent Subjects: A High-Resolution PET [11C]ABP688 Study
    Milella, Michele
    Marengo, Laura
    Larcher, Kevin
    Fotros, Aryandokht
    Dagher, Alain
    Rosa-Neto, Pedro
    Benkelfat, Chawki
    Leyton, Marco
    NEUROPSYCHOPHARMACOLOGY, 2013, 38 : S216 - S216
12345