Studies on the synthesis and reactivity of novel benzofuran-2-yl-[3-methyl-3-phenylcyclobutyl] methanones and their antimicrobial activity

被引:15
|
作者
Koca, M
Ahmedzade, M
Cukurovali, A [1 ]
Kazaz, C
机构
[1] Firat Univ, Fac Arts & Sci, Dept Chem, TR-23119 Elazig, Turkey
[2] Ataturk Univ, Fac Arts & Scu, Dept Chem, Erzurum, Turkey
关键词
furans; cyclobutane; oxime; thiazole; thiosemicarbazone;
D O I
10.3390/10070747
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Preparation in excellent yields of cyclobutyl benzofuran-2-yl- and naphthofuran-2-yl-ketones, the corresponding ketoximes and thiosemicarbazones, ether derivatives of the ketoximes and thiazoles derived from the thiosernicarbazones are described. Two of the synthesized compounds have been tested against eight different microorganisms and found to be active against some of the species studied.
引用
收藏
页码:747 / 754
页数:8
相关论文
共 50 条
  • [21] Solvent-free microwave assisted synthesis of substituted (E)-phenyl{3-(2-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]vinyl)benzofuran-2-yl}methanones and their antimicrobial activity
    Ashok, D.
    Ziauddin, M.
    Lakshmi, B. V.
    Sarasija, M.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (04) : 857 - 862
  • [22] Solvent-free microwave assisted synthesis of substituted (E)-phenyl{3-(2-[1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl]vinyl)benzofuran-2-yl}methanones and their antimicrobial activity
    D. Ashok
    M. Ziauddin
    B. V. Lakshmi
    M. Sarasija
    Russian Journal of General Chemistry, 2017, 87 : 857 - 862
  • [23] Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes
    Benkli, K
    Gündogdu-Karaburun, N
    Karaburun, AÇ
    Uçucu, Ü
    Demirayak, S
    Kiraz, N
    ARCHIVES OF PHARMACAL RESEARCH, 2003, 26 (03) : 202 - 206
  • [24] Synthesis and antifungal activities of some aryl (3-methyl-benzofuran-2-yl) ketoximes
    Kadriye Benkli
    Nalan Gündoĝdu-Karaburun
    Ahmet çaĝri Karaburun
    ümit Uçucu
    Sseref Demirayak
    Nuri Kiraz
    Archives of Pharmacal Research, 2003, 26 : 202 - 206
  • [25] SYNTHESIS AND CHARACTERIZATION OF SELECTED METHYL 5-METHOXY-2-METHYL-1-BENZOFURAN-3-CARBOXYLATE DERIVATIVES WITH POTENTIAL ANTIMICROBIAL ACTIVITY
    Krawiecka, Mariola
    Kuran, Bozena
    Kossakowski, Jerzy
    Wolska, Irena
    Kierzkowska, Marta
    Mlynarczyk, Grazyna
    ACTA POLONIAE PHARMACEUTICA, 2012, 69 (06): : 1055 - 1065
  • [26] Convenient Synthesis and Antimicrobial Activity of New 3-Substituted 5-(Benzofuran-2-yl)-pyrazole Derivatives
    Abdel-Wahab, Bakr F.
    Abdel-Aziz, Hatem A.
    Ahmed, Essam M.
    ARCHIV DER PHARMAZIE, 2008, 341 (11) : 734 - 739
  • [27] Structural and spectroscopic characterization of 4-(3-methyl-3-phenylcyclobutyl)-2-(2-propylidenehydrazinyl)thiazole: A combined experimental and DFT analysis
    Sen, Fatih
    Dincer, Muharrem
    Cukurovali, Alaaddin
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2015, 150 : 257 - 267
  • [28] Crystal structure and Hirshfeld surface analysis of (Z)-4-{[4-(3-methyl-3-phenylcyclobutyl)thiazol-2-yl]amino}-4-oxobut-2-enoic acid
    Simsek, Okan
    Dincer, Muharrem
    Dege, Necmi
    Saif, Eiad
    Yilmaz, Ibrahim
    Cukurovali, Alaaddin
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2022, 78 : 120 - +
  • [29] Spectroscopic and molecular modeling studies of N-(4-(3-methyl-3-phenylcyclobutyl)-3-phenylthiazole-2(3H)-ylidene)aniline by using experimental and density functional methods
    Sen, Fatih
    Ekici, Oner
    Dincer, Muharrem
    Cukurovali, Alaaddin
    JOURNAL OF SAUDI CHEMICAL SOCIETY, 2017, 21 (04) : 377 - 389
  • [30] Synthesis, spectroscopic, X-ray diffraction and tautomeric properties of 5-(diethylamino)-2-((2-(5-(3-methyl-3-phenylcyclobutyl)-6H-1,3,4-thiadiazin-2yl)hydrazono)methyl)phenol: A combined experimental and theoretical study
    Cukurovali, Alaaddin
    Karakurt, Tuncay
    JOURNAL OF MOLECULAR STRUCTURE, 2019, 1189 : 328 - 337