Recent advances in gene expression using alphavirus vectors

被引：18
|
作者：
Garoff, H [1 ]
Li, KJ [1 ]
机构：
[1] Karolinska Inst, Novum, Dept Biosci, S-14157 Huddinge, Sweden
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 1998年 / 9卷 / 05期
关键词：
D O I：
10.1016/S0958-1669(98)80030-X
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Alphavirus vectors use RNA replication in the cell cytoplasm to direct gene expression. New developments of vectors put persistency of expression and infection of specific cells in focus. Furthermore, a new application shows that the system can be used for production of retrovirus vectors carrying genes with introns and control/regulatory regions.
引用
收藏
页码：464 / 469
页数：6
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