Knockout of CBLB Greatly Enhances Anti-Tumor Activity of CAR T Cells

被引：2

作者：

Hooper, Kathryn ^{[1
]}

Havens, Kyle ^{[1
]}

Krostag, Anne-Rachel ^{[1
]}

Magee, Michael S. ^{[2
]}

Martin, Unja ^{[1
]}

Gupta, Ankit ^{[2
]}

Smurnyy, Yegor ^{[2
]}

Pechilis, Lisa ^{[2
]}

Rode, Amanda ^{[2
]}

Chavkin, Andrew ^{[2
]}

Grande, Shannon ^{[2
]}

Morgan, Richard A. ^{[2
]}

Jarjour, Jordan ^{[1
]}

Astrakhan, Alexander ^{[1
]}

机构：

[1] Bluebird Bio, Seattle, WA USA

[2] Bluebird Bio, Cambridge, MA USA

来源：

BLOOD | 2018年 / 132卷

关键词：

D O I：

10.1182/blood-2018-99-119247

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

338

引用

页数：2

共 50 条

[21] Inducible localized delivery of an anti-PD-1 scFv enhances anti-tumor activity of ROR1 CAR-T cells in TNBC
Micaela Harrasser
Satyen Harish Gohil
Hiu Lau
Marco Della Peruta
Vincent Muczynski
Dominic Patel
Elena Miranda
Kristiana Grigoriadis
Anita Grigoriadis
David Granger
Rachel Evans
Amit Chunilal Nathwani
Breast Cancer Research, 24
[22] Potent In Vivo Transduction by iGPS Particles Generates CAR T Cells with Durable Anti-Tumor Activity
Contrastano, Shannon Grande
Beura, Emily T.
Wong, Denise
Ndakwah, Gabrielle
Latimer, Howard J.
Obrigewitch, Jenifer
Sanabria, Jose
Najibi, Alexander J.
Wambua, Daniel
Wood, Jeff
Murray, Jessica
Lau, Maggie
Figueroa, Josue
Warr, Alyson
Dobson, Connor S.
Perkins, Molly R.
Friedman, Kevin
MOLECULAR THERAPY, 2023, 31 (04) : 48 - 49
[23] Neutrophil depletion enhances the anti-tumor activity of CAR-T cells in an autochthonous model of non-small cell lung cancer
Ortiz-Espinosa, Sergio
Srivastava, Shivani
CANCER IMMUNOLOGY RESEARCH, 2023, 11 (12)
[24] RADIATION PRIMING IMPROVES THE ANTI-TUMOR ACTIVITY OF HER2 CAR T CELLS IN GLIOBLASTOMA
Mullikin, Dolores
Joseph, Sujith
Mathew, Pretty
Salsman, Vita
Sanber, Khaled
Lindsay, Holly
Chakraborty, Rikhia
Gaber, Waleed
Ahmed, Nabil
Hegde, Meena
PEDIATRIC BLOOD & CANCER, 2019, 66
[25] Oncolytic Adenovirus Expressing Cytokines Enhances Anti-Tumor Efficacy of Mesothelin-Redirected CAR-T Cells
Watanabe, Keisuke
Guedan, Sonia
Scholler, John
McGettigan, Shannon
Luo, Yangpin
Tahtinen, Siri
Parviainen, Suvi
Havunen, Riikka
Siurala, Mikko
Hemminki, Akseli
June, Carl H.
BLOOD, 2016, 128 (22)
[26] BANANA LECTIN EXPRESSING CAR T CELLS ENHANCE ANTI-TUMOR ACTIVITY AGAINST HETEROGENOUS SOLID TUMORS
Mckenna, K.
Ozcan, A.
Markovitz, D.
Brenner, M.
HUMAN GENE THERAPY, 2023, 34 (21-22) : A21 - A21
[27] IL-6 trans-signaling promotes the expansion and anti-tumor activity of CAR T cells
Zhiwu Jiang
Rui Liao
Jiang Lv
Shanglin Li
Diwei Zheng
Le Qin
Di Wu
Suimin Chen
Youguo Long
Qiting Wu
Suna Wang
Simiao Lin
Xiaohan Huang
Zhaoyang Tang
Pengcheng Shi
Hongsheng Zhou
Qifa Liu
Ruocong Zhao
Yangqiu Li
Yang Jie
Wei Wei
Peilong Lai
Xin Du
Shuzhong Cui
Robert Weinkove
Pentao Liu
Duanqing Pei
Yao Yao
Peng Li
Leukemia, 2021, 35 : 1380 - 1391
[28] Radiation therapy enhances anti-tumor activity of a MET CAR T-based immunotherapy approach for glioblastoma multiforme.
Hovhannisyan, Lusine
Aebersold, Daniel M.
Maher, John
Ochsenbein, Adrian F.
Riether, Carsten
Medova, Michaela
Zimmer, Yitzhak
CLINICAL CANCER RESEARCH, 2021, 27 (08)
[29] PHARMACOLOGIC INHIBITION OF DGKα ACTIVATES T CELLS AND ENHANCES ANTI-TUMOR IMMUNITY
Wang, Adele
Stapleton, Lance
Belzie, Jean-Philippe
Xing, Weimei
Muiru, Gladys
Kornyeyev, Dmytro
Hsieh, Edward
Liclican, Albert
Toy, Pamela
Xu, Mengshu
Kim, Kei
Lee, Jacob
Kuhne, Michelle
Lad, Latesh
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A1108 - A1108
[30] IL-6 trans-signaling promotes the expansion and anti-tumor activity of CAR T cells
Jiang, Zhiwu
Liao, Rui
Lv, Jiang
Li, Shanglin
Zheng, Diwei
Qin, Le
Wu, Di
Chen, Suimin
Long, Youguo
Wu, Qiting
Wang, Suna
Lin, Simiao
Huang, Xiaohan
Tang, Zhaoyang
Shi, Pengcheng
Zhou, Hongsheng
Liu, Qifa
Zhao, Ruocong
Li, Yangqiu
Jie, Yang
Wei, Wei
Lai, Peilong
Du, Xin
Cui, Shuzhong
Weinkove, Robert
Liu, Pentao
Pei, Duanqing
Yao, Yao
Li, Peng
LEUKEMIA, 2021, 35 (05) : 1380 - 1391

← 1 2 3 4 5 →