Wave propagation in cardiac tissue and effects of intracellular calcium dynamics (computer simulation study)

被引：22
|
作者：
Chudin, E
Garfinkel, A
Weiss, J
Karplus, W
Kogan, B
机构：
[1] Univ Calif Los Angeles, Dept Biomath, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Cardiol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Dept Comp Sci, Los Angeles, CA 90095 USA
来源：
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 1998年 / 69卷 / 2-3期
关键词：
D O I：
10.1016/S0079-6107(98)00009-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Computer simulation using Luo-Rudy I1 model of ventricular myocyte showed that intracellular calcium dynamics become irregular in case of high rate stimulation. This causes the transition from stationary to nonstationary spiral wave and its breakup in 2D model of cardiac tissue. Obtained results suggest how ventricular fibrillation may occur due to the abnormalities of intracellular calcium dynamics. The short review of existing cardiac cell models with calcium dynamics is presented. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：225 / 236
页数：12
相关论文
共 50 条
  • [31] Simulation of wave propagation effects in machine windings
    De Gersem, Herbert
    Henze, Olaf
    Weiland, Thomas
    Binder, Andreas
    COMPEL-THE INTERNATIONAL JOURNAL FOR COMPUTATION AND MATHEMATICS IN ELECTRICAL AND ELECTRONIC ENGINEERING, 2010, 29 (01) : 23 - 38
  • [32] The role of heterogeneities and intercellular coupling in wave propagation in cardiac tissue
    Steinberg, BE
    Glass, L
    Shrier, A
    Bub, G
    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2006, 364 (1842): : 1299 - 1311
  • [33] INTRACELLULAR-LOCALIZATION OF THE CALCIUM-ANTAGONIST PROPYLMETHYLENEDIOXYINDENE IN CARDIAC TISSUE
    LYNCH, JJ
    RAHWAN, RG
    FEDERATION PROCEEDINGS, 1983, 42 (05) : 1359 - 1359
  • [34] A MODEL STUDY OF THE EFFECTS OF THE DISCRETE CELLULAR STRUCTURE ON ELECTRICAL PROPAGATION IN CARDIAC TISSUE
    RUDY, Y
    QUAN, WL
    CIRCULATION RESEARCH, 1987, 61 (06) : 815 - 823
  • [35] Effects of tissue fibrosis on, propagation of cardiac electrical activity: a theoretical study.
    Comtois, Philippe
    Nattel, Stanley
    BIOPHYSICAL JOURNAL, 2007, : 623A - 623A
  • [36] Role of intracellular calcium dynamics in the short-term memory in CVM model: A simulation study
    Mei, Xi
    Wang, Jing
    Mei, Jian-sheng
    Zhang, Hong
    Zhang, Zhen-xi
    COMPUTERS IN BIOLOGY AND MEDICINE, 2011, 41 (04) : 206 - 210
  • [37] The effects of hypervolemia on cardiac function a computer simulation
    Kong, A
    Bai, J
    Zhou, XQ
    PROCEEDINGS OF THE 18TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOL 18, PTS 1-5, 1997, 18 : 1717 - 1718
  • [38] Dynamical effects of diffusive cell coupling on cardiac excitation and propagation: a simulation study
    Qu, ZL
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2004, 287 (06): : H2803 - H2812
  • [39] Simulation study on the effects of cancellous bone structure in the skull on ultrasonic wave propagation
    Michimoto, Itsuki
    Miyashita, Kazuki
    Suzuyama, Hidehisa
    Yano, Keita
    Kobayashi, Yasuyo
    Saito, Kozue
    Matsukawa, Mami
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [40] Stochastic Termination of Spiral Wave Dynamics in Cardiac Tissue
    Rappel, Wouter-Jan
    Krummen, David E.
    Baykaner, Tina
    Zaman, Junaid
    Donsky, Alan
    Swarup, Vijay
    Miller, John M.
    Narayan, Sanjiv M.
    FRONTIERS IN NETWORK PHYSIOLOGY, 2022, 2
12345