The Hsp90 inhibitor ganetespib overcomes EGFR-based intratumoral heterogeneity to block glioma proliferation

被引：0
|
作者：
Driscoll, James J. [1 ]
Narayanan, Nitin S. [1 ]
Jagannathan, Sajjeev [1 ]
机构：
[1] Univ Cincinnati, Cincinnati, OH USA
来源：
CANCER RESEARCH | 2014年 / 74卷 / 19期
关键词：
D O I：
10.1158/1538-7445.AM2014-LB-140
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
LB-140
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Intratumoral heterogeneity for hsp90 beta mRNA levels in a breast cancer cell line
    Luparello, C
    Noel, A
    PucciMinafra, I
    DNA AND CELL BIOLOGY, 1997, 16 (10) : 1231 - 1236
  • [22] Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer
    Lang, Julie E.
    Forero-Torres, Andres
    Yee, Douglas
    Yau, Christina
    Wolf, Denise
    Park, John
    Parker, Barbara A.
    Chien, A. Jo
    Wallace, Anne M.
    Murthy, Rashmi
    Albain, Kathy S.
    Ellis, Erin D.
    Beckwith, Heather
    Haley, Barbara B.
    Elias, Anthony D.
    Boughey, Judy C.
    Yung, Rachel L.
    Isaacs, Claudine
    Clark, Amy S.
    Han, Hyo S.
    Nanda, Rita
    Khan, Qamar J.
    Edmiston, Kristen K.
    Stringer-Reasor, Erica
    Price, Elissa
    Joe, Bonnie
    Liu, Minetta C.
    Brown-Swigart, Lamorna
    Petricoin, Emanuel F.
    Wulfkuhle, Julia D.
    Buxton, Meredith
    Clennell, Julia L.
    Sanil, Ashish
    Berry, Scott
    Asare, Smita M.
    Wilson, Amy
    Hirst, Gillian L.
    Singhrao, Ruby
    Asare, Adam L.
    Matthews, Jeffrey B.
    Melisko, Michelle
    Perlmutter, Jane
    Rugo, Hope S.
    Symmans, W. Fraser
    van't Veer, Laura J.
    Hylton, Nola M.
    DeMichele, Angela M.
    Berry, Donald A.
    Esserman, Laura J.
    NPJ BREAST CANCER, 2022, 8 (01)
  • [23] MECHANISM(S) OF ACTION AND POTENCY OF HSP90 INHIBITOR GANETESPIB IN SMALL CELL LUNG CARCINOMA CELLS
    Lee, Dae Ho
    Lai, Chien-Hao
    Wang, Yisong
    Giaccone, Giuseppe
    JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (06) : S936 - S937
  • [24] Phase 1 Study of HSP90 Inhibitor Ganetespib with Pemetrexed and Cisplatin/Carboplatin Chemotherapy for Pleural Mesothelioma
    Fennell, D.
    Danson, S.
    Forster, M.
    Talbot, D.
    Woll, P.
    Child, J.
    Ngai, Y.
    Farrelly, L.
    Hackshaw, A.
    Sharkey, A.
    Busacca, S.
    Hastings, R.
    Barnes, D.
    Nicolson, M.
    Taylor, P.
    Ahmed, S.
    Wheeler, G.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S397 - S397
  • [25] HSP90 Inhibitor Ganetespib Enhances the Sensitivity of Mantle Cell Lymphoma to Bruton's Tyrosine Kinase Inhibitor Ibrutinib
    Lu, Ziwen
    Wang, Zhixin
    Tu, Zhigang
    Liu, Hanqing
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [26] Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer
    Julie E. Lang
    Andres Forero-Torres
    Douglas Yee
    Christina Yau
    Denise Wolf
    John Park
    Barbara A. Parker
    A. Jo Chien
    Anne M. Wallace
    Rashmi Murthy
    Kathy S. Albain
    Erin D. Ellis
    Heather Beckwith
    Barbara B. Haley
    Anthony D. Elias
    Judy C. Boughey
    Rachel L. Yung
    Claudine Isaacs
    Amy S. Clark
    Hyo S. Han
    Rita Nanda
    Qamar J. Khan
    Kristen K. Edmiston
    Erica Stringer-Reasor
    Elissa Price
    Bonnie Joe
    Minetta C. Liu
    Lamorna Brown-Swigart
    Emanuel F. Petricoin
    Julia D. Wulfkuhle
    Meredith Buxton
    Julia L. Clennell
    Ashish Sanil
    Scott Berry
    Smita M. Asare
    Amy Wilson
    Gillian L. Hirst
    Ruby Singhrao
    Adam L. Asare
    Jeffrey B. Matthews
    Michelle Melisko
    Jane Perlmutter
    Hope S. Rugo
    W. Fraser Symmans
    Laura J. van ‘t Veer
    Nola M. Hylton
    Angela M. DeMichele
    Donald A. Berry
    Laura J. Esserman
    npj Breast Cancer, 8
  • [27] HSP90 inhibition overcomes EGFR amplification-induced resistance to third-generation EGFR-TKIs
    Watanabe, Sho
    Goto, Yasushi
    Yasuda, Hiroyuki
    Kohno, Takashi
    Motoi, Noriko
    Ohe, Yuichiro
    Nishikawa, Hiroyoshi
    Kobayashi, Susumu S.
    Kuwano, Kazuyoshi
    Togashi, Yosuke
    THORACIC CANCER, 2021, 12 (05) : 631 - 642
  • [28] Targeting KRAS-Mutant Non-Small Cell Lung Cancer with the Hsp90 Inhibitor Ganetespib
    Acquaviva, Jaime
    Smith, Donald L.
    Sang, Jim
    Friedland, Julie C.
    He, Suqin
    Sequeira, Manuel
    Zhang, Chaohua
    Wada, Yumiko
    Proia, David A.
    MOLECULAR CANCER THERAPEUTICS, 2012, 11 (12) : 2633 - 2643
  • [29] Synergistic activity of the Hsp90 inhibitor ganetespib with taxanes in non-small cell lung cancer models
    David A. Proia
    Jim Sang
    Suqin He
    Donald L. Smith
    Manuel Sequeira
    Chaohua Zhang
    Yuan Liu
    Shuxia Ye
    Dan Zhou
    Ronald K. Blackman
    Kevin P. Foley
    Keizo Koya
    Yumiko Wada
    Investigational New Drugs, 2012, 30 : 2201 - 2209
  • [30] Preclinical Activity Profile and Therapeutic Efficacy of the HSP90 Inhibitor Ganetespib in Triple-Negative Breast Cancer
    Proia, David A.
    Zhang, Chaohua
    Sequeira, Manuel
    Jimenez, John-Paul
    He, Suqin
    Spector, Neil
    Shapiro, Geoffrey I.
    Tolaney, Sara
    Nagai, Masazumi
    Acquaviva, Jaime
    Smith, Donald L.
    Sang, Jim
    Bates, Richard C.
    El-Hariry, Iman
    CLINICAL CANCER RESEARCH, 2014, 20 (02) : 413 - 424
12345