Ionic-liquid-supported total synthesis of sansalvamide a peptide

被引:19
|
作者
Chen, Ling [1 ]
Zheng, Mingfang [1 ]
Zhou, Yu [1 ,2 ]
Liu, Hong [1 ]
Jiang, Hualiang [1 ,3 ]
机构
[1] Shanghai Inst Biol Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Ctr Drug Discovery & Design, Shanghai, Peoples R China
[2] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang, Liaoning, Peoples R China
[3] E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
基金
中国国家自然科学基金;
关键词
ionic liquid; sansalvamide A peptide; total synthesis;
D O I
10.1080/00397910701749633
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile and efficient total synthesis of bioactive sansalvamide A peptide has been accomplished, including the-ionic-liquid supported method and final PyBOP-promoted ring closure.
引用
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页码:239 / 248
页数:10
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