Expression of the organic anion transporters OATP1B1, OATP1B3, and OATP2B1 in human liver is affected by genetic and nongenetic factors

被引：0
|
作者：
Nies, A. [1 ]
Winter, S. [1 ]
Burk, O. [1 ]
Klein, K. [1 ]
Zanger, U. M. [1 ]
Stieger, B. [2 ]
Schwab, M. [1 ,3 ]
Schaeffeler, E. [1 ]
机构：
[1] Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany
[2] Univ Spital Zurich, Klin Klin Pharmakol & Toxikol, Zurich, Switzerland
[3] Univ Tubingen, Klin Pharmakol Abt, Tubingen, Germany
来源：
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 2011年 / 383卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：80 / 80
页数：1
相关论文
共 50 条
  • [31] The effect of well-known inhibitors of efflux transporters on the uptake transporters, OATP1B1 and OATP1B3
    Matsushima, Soichiro
    Maeda, Kazuya
    Sugiyama, Yuichi
    DRUG METABOLISM REVIEWS, 2006, 38 : 60 - 61
  • [32] Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel
    Iusuf, Dilek
    Hendrikx, Jeroen J. M. A.
    van Esch, Anita
    de Steeg, Evita van
    Wagenaar, Els
    Rosing, Hilde
    Beijnen, Jos H.
    Schinkel, Alfred H.
    INTERNATIONAL JOURNAL OF CANCER, 2015, 136 (01) : 225 - 233
  • [33] Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans
    Hirano, M
    Maeda, K
    Shitara, Y
    Sugiyama, Y
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2004, 311 (01): : 139 - 146
  • [34] The Effect of Original Russian Neurotropic Drugs on Organic Anion Transporting Polypeptides OATP1B1 and OATP1B3
    Erokhina, P. D.
    Abalenikhina, Yu. V.
    Mylnikov, P. Yu.
    Petrov, A. V.
    Ganina, S. O.
    Konyakhin, E. A.
    Shchulkin, A. V.
    Yakusheva, E. N.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2023, 176 (02) : 170 - 175
  • [35] Suppression of OATP1B1, OATP1B3, and OATP 2B1 transporters in primary cryopreserved human hepatocytes following lipid delivery of stealth siRNA
    Grepper, Susan
    Vozza-Brown, Laura
    Sahi, Jasminder
    DRUG METABOLISM REVIEWS, 2009, 41 : 175 - 176
  • [36] Organic Anion Transporting Polypeptide 1B1 (OATP1B1) and OATP1B3: Genetic Variability and Haplotype Analysis in White Canadians
    Boivin, Andree-Anne
    Cardinal, Heloise
    Barama, Azemi
    Pichette, Vincent
    Hebert, Marie-Josee
    Roger, Michel
    DRUG METABOLISM AND PHARMACOKINETICS, 2010, 25 (05) : 508 - 515
  • [37] Fluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3
    Bednarczyk, Dallas
    ANALYTICAL BIOCHEMISTRY, 2010, 405 (01) : 50 - 58
  • [38] Further Characterization of the Electrogenicity and pH Sensitivity of the Human Organic Anion-Transporting Polypeptides OATP1B1 and OATP1B3
    Martinez-Becerra, Pablo
    Briz, Oscar
    Romero, Marta R.
    Macias, Rocio I. R.
    Perez, Maria J.
    Sancho-Mateo, Carlos
    Lostao, Maria P.
    Fernandez-Abalos, Jose M.
    Marin, Jose J. G.
    MOLECULAR PHARMACOLOGY, 2011, 79 (03) : 596 - 607
  • [39] Influence of Human OATP1B1, OATP1B3, and OATP1A2 on the Pharmacokinetics of Methotrexate and Paclitaxel in Humanized Transgenic Mice
    van de Steeg, Evita
    van Esch, Anita
    Wagenaar, Els
    Kenworthy, Kathryn E.
    Schinkel, Alfred H.
    CLINICAL CANCER RESEARCH, 2013, 19 (04) : 821 - 832
  • [40] OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP
    Zhang, Yuchen
    Ruggiero, Melissa
    Hagenbuch, Bruno
    DRUG METABOLISM AND DISPOSITION, 2020, 48 (08) : 622 - 630
12345