Expression of the organic anion transporters OATP1B1, OATP1B3, and OATP2B1 in human liver is affected by genetic and nongenetic factors

被引:0
|
作者
Nies, A. [1 ]
Winter, S. [1 ]
Burk, O. [1 ]
Klein, K. [1 ]
Zanger, U. M. [1 ]
Stieger, B. [2 ]
Schwab, M. [1 ,3 ]
Schaeffeler, E. [1 ]
机构
[1] Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany
[2] Univ Spital Zurich, Klin Klin Pharmakol & Toxikol, Zurich, Switzerland
[3] Univ Tubingen, Klin Pharmakol Abt, Tubingen, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:80 / 80
页数:1
相关论文
共 50 条
  • [1] COMPREHENSIVE ANALYSIS OF GENETIC AND NON-GENETIC FACTORS AFFECTING EXPRESSION OF THE ORGANIC ANION TRANSPORTERS OATP1B1, OATP1B3, AND OATP2B1 IN HUMAN LIVER
    Nies, Anne T.
    Winter, Stefan
    Burk, Oliver
    Klein, Kathrin
    Zanger, Ulrich M.
    Stieger, Bruno
    Schwab, Matthias
    Schaeffeler, Elke
    HEPATOLOGY, 2010, 52 (04) : 433A - 433A
  • [2] Structure of human drug transporters OATP1B1 and OATP1B3
    Anca-Denise Ciută
    Kamil Nosol
    Julia Kowal
    Somnath Mukherjee
    Ana S. Ramírez
    Bruno Stieger
    Anthony A. Kossiakoff
    Kaspar P. Locher
    Nature Communications, 14
  • [3] Structure of human drug transporters OATP1B1 and OATP1B3
    Ciuta, Anca-Denise
    Nosol, Kamil
    Kowal, Julia
    Mukherjee, Somnath
    Ramirez, Ana S.
    Stieger, Bruno
    Kossiakoff, Anthony A.
    Locher, Kaspar P.
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [4] Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1
    Anne T Nies
    Mikko Niemi
    Oliver Burk
    Stefan Winter
    Ulrich M Zanger
    Bruno Stieger
    Matthias Schwab
    Elke Schaeffeler
    Genome Medicine, 5
  • [5] Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1
    Nies, Anne T.
    Niemi, Mikko
    Burk, Oliver
    Winter, Stefan
    Zanger, Ulrich M.
    Stieger, Bruno
    Schwab, Matthias
    Schaeffeler, Elke
    GENOME MEDICINE, 2013, 5
  • [6] Interaction of Sulfonylureas with Liver Uptake Transporters OATP1B1 and OATP1B3
    Chen, Yu
    Chen, Lin
    Zhang, Hong
    Huang, Shibo
    Xiong, Yuqing
    Xia, Chunhua
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 123 (02) : 147 - 154
  • [7] Characterization of Ursodeoxycholic and Norursodeoxycholic Acid as Substrates of the Hepatic Uptake Transporters OATP1B1, OATP1B3, OATP2B1 and NTCP
    Koenig, Joerg
    Klatt, Sabine
    Dilger, Karin
    Fromm, Martin F.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2012, 111 (02) : 81 - 86
  • [8] Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3
    Yamaguchi, Hiroaki
    Okada, Masahiro
    Akitaya, Shou
    Ohara, Hiroshi
    Mikkaichi, Tsuyoshi
    Ishikawa, Haruna
    Sato, Mayumi
    Matsuura, Masaki
    Saga, Toshihide
    Unno, Michiaki
    Abe, Takaaki
    Mano, Nariyasu
    Hishinuma, Takanori
    Goto, Junichi
    JOURNAL OF LIPID RESEARCH, 2006, 47 (06) : 1196 - 1202
  • [9] Nuclear receptor ligands interact with the human liver transporters OATP1B1 and OATP1B3
    Hagenbuch, BH
    Obaidat, A
    Thompson, L
    FASEB JOURNAL, 2006, 20 (05): : A1143 - A1143
  • [10] Interaction of deoxyschizandrin and schizandrin B with liver uptake transporters OATP1B1 and OATP1B3
    Lu, Yanli
    Hu, Qingqing
    Chen, Lin
    Zhang, Hong
    Huang, Shibo
    Xiong, Yuqing
    Xia, Chunhua
    XENOBIOTICA, 2019, 49 (02) : 239 - 246