Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas

被引：30

作者：

Kim, Lawrence H. C. ^{[1
]}

Hogeling, Marcia ^{[2
]}

Wargon, Orli ^{[2
]}

Jiwane, Ashish ^{[1
]}

Adams, Susan ^{[1
]}

机构：

[1] Sydney Childrens Hosp, Dept Pediat Surg, Randwick, NSW, Australia

[2] Sydney Childrens Hosp, Dept Pediat Dermatol, Randwick, NSW, Australia

来源：

JOURNAL OF PEDIATRIC SURGERY | 2011年 / 46卷 / 04期

关键词：

Ulceration; Infantile hemangioma; Propranolol; PULSED-DYE-LASER; CAPILLARY ENDOTHELIAL-CELLS; GROWTH-FACTOR; CLINICAL CHARACTERISTICS; CUTANEOUS HEMANGIOMAS; INFANCY; MANAGEMENT; COMPLICATIONS; INVOLUTION; APOPTOSIS;

D O I：

10.1016/j.jpedsurg.2011.01.012

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Infantile hemangioma (IH) is the most common vascular tumor in early childhood. Ulceration is the most frequent complication, and its management can be challenging. We present 6 cases of ulcerated IH at a single pediatric center, which responded to oral propranolol within 2 to 6 weeks. We recommend that oral propranolol therapy be considered for the management of ulcerated IH as first-line treatment. Crown Copyright (C) 2011 Published by Elsevier Inc. All rights reserved.

引用

页码：759 / 763

页数：5

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