Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas

被引:30
|
作者
Kim, Lawrence H. C. [1 ]
Hogeling, Marcia [2 ]
Wargon, Orli [2 ]
Jiwane, Ashish [1 ]
Adams, Susan [1 ]
机构
[1] Sydney Childrens Hosp, Dept Pediat Surg, Randwick, NSW, Australia
[2] Sydney Childrens Hosp, Dept Pediat Dermatol, Randwick, NSW, Australia
关键词
Ulceration; Infantile hemangioma; Propranolol; PULSED-DYE-LASER; CAPILLARY ENDOTHELIAL-CELLS; GROWTH-FACTOR; CLINICAL CHARACTERISTICS; CUTANEOUS HEMANGIOMAS; INFANCY; MANAGEMENT; COMPLICATIONS; INVOLUTION; APOPTOSIS;
D O I
10.1016/j.jpedsurg.2011.01.012
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Infantile hemangioma (IH) is the most common vascular tumor in early childhood. Ulceration is the most frequent complication, and its management can be challenging. We present 6 cases of ulcerated IH at a single pediatric center, which responded to oral propranolol within 2 to 6 weeks. We recommend that oral propranolol therapy be considered for the management of ulcerated IH as first-line treatment. Crown Copyright (C) 2011 Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:759 / 763
页数:5
相关论文
共 50 条
  • [1] Propranolol for treatment of ulcerated infantile hemangiomas
    Saint-Jean, Melanie
    Leaute-Labreze, Christine
    Mazereeuw-Hautier, Juliette
    Bodak, Nathalie
    Hamel-Teillac, Dominique
    Kupfer-Bessaguet, Ingrid
    Lacour, Jean-Philippe
    Naouri, Michael
    Vabres, Pierre
    Hadj-Rabia, Smail
    Nguyen, Jean-Michel
    Stalder, Jean-Francois
    Barbarot, Sebastien
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2011, 64 (05) : 827 - 832
  • [2] Propranolol versus steroids for the treatment of ulcerated infantile hemangiomas
    Polites, Stephanie F.
    Rodrigue, Bentley B.
    Chute, Carol
    Hammill, Adrienne
    Dasgupta, Roshni
    PEDIATRIC BLOOD & CANCER, 2018, 65 (10)
  • [3] Propranolol for the treatment of ulcerated infantile hemangiomas: A prospective study
    Ji, Yi
    Yang, Kaiying
    Zhou, Jiangyuan
    Zhang, Xuepeng
    Xiang, Bo
    Jiang, Xian
    Xu, Xuewen
    Qiu, Tong
    Dai, Shiyi
    Kong, Feiteng
    Lu, Guoyan
    Qiu, Qingxia
    Zhang, Yongbo
    Chen, Siyuan
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2022, 86 (05) : 1149 - 1151
  • [4] Therapeutic efficacy of propranolol for infantile hemangiomas
    Wu, Wenli
    Wang, Hongtao
    Hao, Jiansuo
    Gao, Zijun
    Li, Fan
    Chen, Yiyang
    ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 2019, 128 (02): : 132 - 138
  • [5] PROPRANOLOL FOR THE TREATMENT OF INFANTILE HEMANGIOMAS
    Hammill, Adrienne
    Chute, Carol
    Gupta, Anita
    Lucky, Anne
    Elluru, Ravindhra
    Murrell, Zaria
    Dasgupta, Roshni
    Azizkhan, Richard
    Adams, Denise
    PEDIATRIC BLOOD & CANCER, 2011, 56 (06) : 907 - 908
  • [6] Propranolol treatment for infantile hemangiomas
    Buckmiller, Lisa M.
    CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY, 2009, 17 (06): : 458 - 459
  • [7] Propranolol in the Treatment of Infantile Hemangiomas
    Tan, Xin
    Guo, Shu
    Wang, Chenchao
    CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY, 2021, 14 : 1155 - 1163
  • [8] Propranolol for treatment of infantile hemangiomas
    de Melo, Juliana Nakano
    Rotter, Anita
    Rivitti-Machado, Maria Cecilia
    Prado de Oliveira, Zilda Najjar
    ANAIS BRASILEIROS DE DERMATOLOGIA, 2013, 88 (06) : 220 - 223
  • [9] Propranolol for Surgeons in the Treatment of Infantile Hemangiomas
    Sinha, Shiba
    Lloyd, Mark Sheldon
    JOURNAL OF CRANIOFACIAL SURGERY, 2020, 31 (01) : 134 - 137
  • [10] Propranolol for the Treatment of Orbital Infantile Hemangiomas
    Fridman, Gretta
    Grieser, Eric
    Hill, Robert
    Khuddus, Nausheen
    Bersani, Tom
    Slonim, Charles
    OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, 2011, 27 (03): : 190 - 194