Two new lignans with their biological activities in Portulaca oleracea L.

被引：7
|
作者：
Wang, Chengyu [1 ]
Guo, Shengnan [1 ]
Tian, Jiayin [1 ]
Liu, Peishan [1 ]
Song, Mingyang [1 ]
Zhang, Wenjie [1 ,2 ]
Ying, Xixiang [1 ,2 ]
机构：
[1] Liaoning Univ Tradit Chinese Med, Sch Pharm, Dalian, Peoples R China
[2] Liaoning Univ Tradit Chinese Med, Sch Pharm, 77, Shengming 1 Rd, DD Port, Dalian 116600, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2022年 / 50卷
基金：
中国国家自然科学基金;
关键词：
Portulaca oleracea L; Oleralignan; Lignan; Anti-inflammatory activity; Antioxidant activity; POLYSACCHARIDE; CELLS;
D O I：
10.1016/j.phytol.2022.06.003
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new lignans, identified as 6,7-dihydroxy-4-(4 ''-hydroxy-3 ''-methoxyphenyl)-2-naphthoic acid, named Oleralignan C (1), and 4-(3,4-dihydroxyphenyl)-6-hydroxy-7-methoxy-2-naphthoic acid, named Oleralignan D (2), were obtained from Portulaca oleracea L. The structures were determined by spectroscopic methods, including UHPLC-ESI-QTOFMS, D-1 and D-2 NMR. Both Oleralignan C (1) and Oleralignan D (2) inhibited the inflammatory factors, IL-1 beta and TNF-alpha in RAW 264.7 cells induced by lipopolysaccharide (LPS). Both compounds also could clear 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radicals indicating their antioxidant potential.
引用
收藏
页码：95 / 99
页数：5
相关论文
共 50 条
  • [31] A novel alkaloid from Portulaca oleracea L.
    Xu, Liang
    Ying, Zheming
    Wei, Wenjuan
    Hao, Dong
    Wang, Haibo
    Zhang, Wenjie
    Li, Cuiyu
    Jiang, Mingyue
    Ying, Xixiang
    Liu, Jing
    NATURAL PRODUCT RESEARCH, 2017, 31 (08) : 902 - 908
  • [32] An isoindole alkaloid from Portulaca oleracea L.
    Jiang, Mingyue
    Zhang, Wenjie
    Yang, Xu
    Xiu, Fen
    Xu, Haoran
    Ying, Xixiang
    Stien, Didier
    NATURAL PRODUCT RESEARCH, 2018, 32 (20) : 2431 - 2436
  • [33] A new lactam alkaloid from Portulaca oleracea L. and its cytotoxity
    Zhao, Chengcheng
    Ying, Zheming
    Tao, Xiaojun
    Jiang, Mingyue
    Ying, Xixiang
    Yang, Guanlin
    NATURAL PRODUCT RESEARCH, 2018, 32 (13) : 1548 - 1553
  • [34] A new homoisoflavone from Portulaca oleracea L. and its antioxidant activity
    Yang, Xu
    Ying, Zheming
    Liu, Hairong
    Ying, Xixiang
    Yang, Guanlin
    NATURAL PRODUCT RESEARCH, 2019, 33 (24) : 3500 - 3506
  • [35] A new alkaloid from Portulaca oleracea L. and its antiacetylcholinesterase activity
    Xiu, Fen
    Li, Xuetao
    Zhang, Wenjie
    He, Fan
    Ying, Xixiang
    Stien, Didier
    NATURAL PRODUCT RESEARCH, 2019, 33 (18) : 2583 - 2590
  • [36] Two new metabolites from Portulaca oleracea and their anti-inflammatory activities
    Tian, Jiayin
    Ying, Ziyue
    Lan, Xiujuan
    Li, Yongjie
    Leng, Aijing
    Ying, Xixiang
    PHYTOCHEMISTRY LETTERS, 2022, 48 : 114 - 119
  • [37] Portulaca oleracea L.: A Review of Phytochemistry and Pharmacological Effects
    Zhou, Yan-Xi
    Xin, Hai-Liang
    Rahman, Khalid
    Wang, Su-Juan
    Peng, Cheng
    Zhang, Hong
    BIOMED RESEARCH INTERNATIONAL, 2015, 2015
  • [38] Sulfated modification and cytotoxicity of Portulaca oleracea L. polysaccharides
    Chen, Tong
    Wang, Jin
    Li, Yuanyuan
    Shen, Jianmin
    Zhao, Ting
    Zhang, Haixia
    GLYCOCONJUGATE JOURNAL, 2010, 27 (06) : 635 - 642
  • [39] Utilization of Portulaca Oleracea L. to Improve Quality of Yoghurt
    Sallam, E. M.
    Anwar, M. M.
    ARAB JOURNAL OF NUCLEAR SCIENCES AND APPLICATIONS, 2015, 48 (04): : 208 - 218
  • [40] Surface and emulsification properties of a new gum extracted from Portulaca oleracea L.
    Garti, N
    Slavin, Y
    Aserin, A
    FOOD HYDROCOLLOIDS, 1999, 13 (02) : 145 - 155
12345