Phenolic constituents from twigs of Aleurites fordii and their biological activities

被引:2
|
作者
Park, Kyoung Jin [1 ]
Suh, Won Se [1 ]
Yoon, Da Hye [2 ]
Kim, Chung Sub [1 ,3 ]
Kim, Sun Yeou [2 ]
Lee, Kang Ro [1 ]
机构
[1] Sungkyunkwan Univ, Sch Pharm, Nat Prod Lab, Suwon 16419, South Korea
[2] Gachon Univ, Coll Pharm, Lab Pharmacognosy, Incheon 21936, South Korea
[3] Sungkyunkwan Univ, Dept Biopharmaceut Convergence, Suwon 16419, South Korea
来源
基金
新加坡国家研究基金会;
关键词
Aleurites fordii; antineuroinflammation; Euphorbiaceae; neolignan glycoside; neuroprotective activity; phenolic compound; AROMATIC CONSTITUENTS; BIOACTIVE TRITERPENOIDS; NEOLIGNAN GLYCOSIDES; LIGNAN GLYCOSIDES; DERIVATIVES; LEAVES; GLANDULOSA; GLUCOSIDE; ALCOHOL; ROOTS;
D O I
10.3762/bjoc.17.151
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Three new neolignan glycosides (1-3), a new phenolic glycoside (15), and a new cyanoglycoside (16) were isolated and character-ized from the twigs of Aleurites fordii together with 14 known analogues (4-14 and 17-19). The structural elucidation of the new compounds was performed through the analysis of their NMR, HRMS, and ECD spectra and by chemical methods. All isolated compounds were tested for their antineuroinflammatory and neuroprotective activities.
引用
收藏
页码:2329 / 2339
页数:11
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