Differential chemosensitivity of tumor components in a malignant oligodendroglioma:: Assessment with diffusion-weighted, perfusion-weighted, and serial volumetric MR imaging

被引:0
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作者
Jäger, HR
Waldman, AD
Benton, C
Fox, N
Rees, J
机构
[1] UCL Natl Hosp Neurol & Neurosurg, Lysholm Dept Neuroradiol, London WC1N 3BG, England
[2] UCL Natl Hosp Neurol & Neurosurg, Inst Neurol, London WC1N 3BG, England
[3] Charing Cross Hosp, Dept Imaging, London, England
基金
英国医学研究理事会;
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中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report the case of malignant oligodendroglioma in a 36-year-old man who underwent diffusion-weighted, perfusion-weighted, and volumetric MR imaging before and after PCV (procarbazine, CCNU, vincristine) chemotherapy. The tumor regions exhibiting a low apparent diffusion coefficient and increased relative cerebral blood volume showed a marked response to chemotherapy and dramatic decrease in volume, whereas the remaining tumor regions showed little change. Diffusion-weighted and perfusion-weighted MR imaging may be helpful in predicting chemosensitivity of glial tumors.
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页码:274 / 278
页数:5
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