Integrated Mach-Zehnder interferometer based on ARROW structures for biosensor applications

被引:85
|
作者
Prieto, F
Sepúlveda, B
Calle, A
Llobera, A
Domínguez, C
Lechuga, LM
机构
[1] CSIC, CNM, IMM, Biosensors Grp, Madrid 28760, Spain
[2] CSIC, CNM, IMB, Biosensors Grp, Barcelona 08193, Spain
关键词
ARROW; evanescent field sensors; Mach-Zehnder interferometer; silicon technology;
D O I
10.1016/S0925-4005(03)00257-0
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The theoretical design, fabrication and characterisation of an evanescent field integrated optical (IO) sensor based on a rib anti-resonant reflecting optical waveguide (ARROW) structure are presented. The optical waveguides are designed to verify two conditions: mono-mode behaviour and high surface sensitivity. The sensor system is fabricated with 'silicon microelectronics technology' and it has been tested as a refractometer with glucose solutions of different refractive indices. The feasibility of applying the sensor for immunosensing is shown with antibody/antigen binding experiments. (C) 2003 Elsevier Science B.V. All rights reserved.
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页码:151 / 158
页数:8
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