Copper(I)-Catalyzed Azide-Alkyne Cycloadditions in Ionic Liquids under Amine-Free Conditions

被引：14
|
作者：
Vecchi, Alessandra [1 ]
Chambery, Angela [2 ]
Chiappe, Cinzia [3 ]
Marra, Alberto [1 ]
Dondoni, Alessandro [1 ]
机构：
[1] Univ Ferrara, Dipartmento Chim, Chim Organ Lab, I-44100 Ferrara, Italy
[2] Univ Naples 2, Dipartimento Sci Vita, I-81100 Caserta, Italy
[3] Univ Pisa, Dipartimento Chim & Chim Ind, I-56126 Pisa, Italy
来源：
SYNTHESIS-STUTTGART | 2010年 / 12期
关键词：
alkynes; azides; carbohydrates; copper; cycloadditions; CARBOHYDRATE-CHEMISTRY; CLICK CHEMISTRY; ADAMANTANE; REACTIVITY; SOLVENTS; GREEN;
D O I：
10.1055/s-0029-1218760
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Copper(I) iodide catalyzed cycloadditions of various combinations of structurally diverse organic azides and terminal alkynes were carried out in a commercially available, polyoxygenated ionic liquid (AMMOENG 100 (TM)) without addition of free amine. Unlike the previously tested ionic liquids, this solvent led exclusively to the 1,4-disubstituted triazole regioisomer.
引用
收藏
页码：2043 / 2048
页数：6
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