Nickel-catalyzed hydrogen-borrowing strategy: chemo-selective alkylation of nitriles with alcohols

被引:49
|
作者
Bera, Sourajit [1 ]
Bera, Atanu [1 ]
Banerjee, Debasis [1 ]
机构
[1] Indian Inst Technol Raarkee, Lab Catalysis & Organ Synth, Dept Chem, Raarkee 247667, Uttarakhand, India
关键词
ONE-POT SYNTHESIS; ALPHA-ALKYLATION; ARYLACETONITRILES; MONOALKYLATION; ACETONITRILE; HYDROTALCITE; EFFICIENT; ACCESS;
D O I
10.1039/d0cc02261f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The first nickel-catalyzed hydrogen-borrowing alkylation of a series of aryl acetonitriles with a variety of aryl, heteroaryl, allylic and alkyl alcohols releasing water as the by-product (>33 examples, up to 90% yield) is reported.
引用
收藏
页码:6850 / 6853
页数:4
相关论文
共 50 条
  • [31] Nickel-catalyzed borrowing hydrogen annulations: access to diversified N-heterocycles
    Yang, Peng
    Zhang, Caili
    Gao, Wen-Chao
    Ma, Yu
    Wang, Xiuhua
    Zhang, Li
    Yue, Jieyu
    Tang, Bo
    CHEMICAL COMMUNICATIONS, 2019, 55 (54) : 7844 - 7847
  • [32] A General Strategy for the Nickel-Catalyzed C-H Alkylation of Anilines
    Ruan, Zhixiong
    Lackner, Sebastian
    Ackermann, Lutz
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (09) : 3153 - 3157
  • [33] Borrowing Hydrogen in Water and Ionic Liquids: Iridium-Catalyzed Alkylation of Amines with Alcohols
    Saidi, Ourida
    Blacker, A. John
    Lamb, Gareth W.
    Marsden, Stephen P.
    Taylor, James E.
    Williams, Jonathan M. J.
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2010, 14 (04) : 1046 - 1049
  • [34] Manganese-Catalyzed C(α)-Alkylation of Oxindoles with Secondary Alcohols via Borrowing Hydrogen
    Rana, Jagannath
    Nagarasu, Palaniyappan
    Subaramanian, Murugan
    Mondal, Akash
    Madhu, Vedichi
    Balaraman, Ekambaram
    ORGANOMETALLICS, 2021, 40 (06) : 627 - 634
  • [35] Cobalt-Catalyzed Synthesis of Aromatic, Aliphatic, and Cyclic Secondary Amines via a "Hydrogen-Borrowing" Strategy
    Yin, Zhiwei
    Zeng, Haisu
    Wu, Jing
    Zheng, Shengping
    Zhang, Guoqi
    ACS CATALYSIS, 2016, 6 (10): : 6546 - 6550
  • [36] Cu(I) mediated hydrogen borrowing strategy for the α-alkylation of aryl ketones with aryl alcohols
    Lawal, Nasir S.
    Ibrahim, Halliru
    Bala, Muhammad D.
    MONATSHEFTE FUR CHEMIE, 2021, 152 (02): : 275 - 285
  • [37] Nickel-Catalyzed N-Alkylation of Acylhydrazines and Arylamines Using Alcohols and Enantioselective Examples
    Yang, Peng
    Zhang, Caili
    Ma, Yu
    Zhang, Caiyun
    Li, Aijie
    Tang, Bo
    Zhou, Jianrong Steve
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 56 (46) : 14702 - 14706
  • [38] Cu(I) mediated hydrogen borrowing strategy for the α-alkylation of aryl ketones with aryl alcohols
    Nasir S. Lawal
    Halliru Ibrahim
    Muhammad D. Bala
    Monatshefte für Chemie - Chemical Monthly, 2021, 152 : 275 - 285
  • [39] Diastereo- and Enantioselective Construction of Spirocycles by Nickel-Catalyzed Cascade Borrowing Hydrogen Cyclization
    Ding, Zhengtian
    Wang, Yiming
    Liu, Wenfeng
    Chen, Yate
    Kong, Wangqing
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 143 (01) : 53 - 59
  • [40] Pd/C-Catalyzed Alkylation of Heterocyclic Nucleophiles with Alcohols through the "Borrowing Hydrogen" Process
    Putra, Anggi Eka
    Oe, Yohei
    Ohta, Tetsuo
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 2015 (35) : 7799 - 7805