We report the case of a 3-year-old boy with classical chronic bullous disease of childhood (CBDC) arising after recent Epstein-Barr virus seroconversion following infectious mononucleosis. The patient also had small red cells and decreased levels of circulating IgA. He received combined treatment with dapsone and prednisone with good results. Our report is the first of CBDC preceded by Epstein-Barr virus seroconversion. The virus may have had an initial immunopathogenic role in the genesis of the bullous eruption.
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Arcispedale S Maria Nuova IRCCS, Unit Dermatol, I-42100 Reggio Emilia, ItalyArcispedale S Maria Nuova IRCCS, Unit Dermatol, I-42100 Reggio Emilia, Italy
Di Lernia, Vito
Mansouri, Yasaman
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Univ Hosp Birmingham, Birmingham, W Midlands, EnglandArcispedale S Maria Nuova IRCCS, Unit Dermatol, I-42100 Reggio Emilia, Italy
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Chi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, TaiwanChi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, Taiwan
Koay, Loh-Beng
Tsai, Sun-Lung
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Chi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, TaiwanChi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, Taiwan
Tsai, Sun-Lung
Sun, Chi-Shu
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Chi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, TaiwanChi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, Taiwan
Sun, Chi-Shu
Wu, Kuan-Ta
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Chi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, TaiwanChi Mei Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Yung Kang, Tainan, Taiwan