Comparative effectiveness research (CER) has impending significance for the field of spine surgery. This article outlines the rationale for comparative effectiveness research and reviews recommended priorities of spinal surgery emphasis. It also examines recent key studies of CER in the spine surgery literature and associated cost-effectiveness studies. It concludes with a discussion of the direction of CER in the spine surgery community. (http://thejns.org/doi/abs/10.3171/2012.4.FOCUS1290)
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Mayo Clin, Knowledge & Encounter Res Unit, Rochester, MN 55905 USA
Mayo Clin, Div Gen Internal Med, Rochester, MN 55905 USAMayo Clin, Knowledge & Encounter Res Unit, Rochester, MN 55905 USA
Wang, Amy T.
Wang, Jeffrey K.
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Mayo Clin, Dept Urol, Rochester, MN 55905 USAMayo Clin, Knowledge & Encounter Res Unit, Rochester, MN 55905 USA
Wang, Jeffrey K.
Montori, Victor M.
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Mayo Clin, Knowledge & Encounter Res Unit, Rochester, MN 55905 USA
Mayo Clin, Div Endocrinol, Rochester, MN 55905 USAMayo Clin, Knowledge & Encounter Res Unit, Rochester, MN 55905 USA
Montori, Victor M.
Murad, Mohammad Hassan
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Mayo Clin, Knowledge & Encounter Res Unit, Rochester, MN 55905 USA
Mayo Clin, Div Prevent Occupat & Aerosp Med, Rochester, MN 55905 USAMayo Clin, Knowledge & Encounter Res Unit, Rochester, MN 55905 USA
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Grp Hlth Res Inst, Seattle, WA 98101 USA
Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Chubak, Jessica
Rutter, Carolyn M.
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Grp Hlth Res Inst, Seattle, WA 98101 USA
Univ Washington, Sch Publ Hlth, Dept Biostat, Seattle, WA 98195 USA
Univ Washington, Sch Publ Hlth, Dept Hlth Serv, Seattle, WA 98195 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Rutter, Carolyn M.
Kamineni, Aruna
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Grp Hlth Res Inst, Seattle, WA 98101 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Kamineni, Aruna
Johnson, Eric A.
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Grp Hlth Res Inst, Seattle, WA 98101 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Johnson, Eric A.
Stout, Natasha K.
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Harvard Univ, Sch Med, Dept Populat Med, Boston, MA USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Stout, Natasha K.
Weiss, Noel S.
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Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA
Fred Hutchinson Canc Res Ctr, Program Epidemiol, Seattle, WA 98104 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Weiss, Noel S.
Doria-Rose, V. Paul
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NCI, Hlth Serv & Econ Branch, Appl Res Program, Div Canc Control & Populat Sci, Bethesda, MD 20892 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Doria-Rose, V. Paul
Doubeni, Chyke A.
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Univ Penn, Perelman Sch Med, Dept Family Med & Community Hlth, Philadelphia, PA 19104 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
Doubeni, Chyke A.
Buist, Diana S. M.
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Grp Hlth Res Inst, Seattle, WA 98101 USA
Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA
Univ Washington, Sch Publ Hlth, Dept Hlth Serv, Seattle, WA 98195 USAGrp Hlth Res Inst, Seattle, WA 98101 USA
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Columbia Univ Coll Phys & Surg, Div Gynecol Oncol, Dept Obstet & Gynecol, New York, NY 10032 USA
Herbert Irving Comprehens Canc Ctr, New York, NY 10032 USAColumbia Univ Coll Phys & Surg, Div Gynecol Oncol, Dept Obstet & Gynecol, New York, NY 10032 USA
Wright, Jason D.
Hershman, Dawn L.
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Columbia Univ Coll Phys & Surg, Dept Med, New York, NY 10032 USA
Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY 10032 USA
Herbert Irving Comprehens Canc Ctr, New York, NY 10032 USAColumbia Univ Coll Phys & Surg, Div Gynecol Oncol, Dept Obstet & Gynecol, New York, NY 10032 USA