Interaction between Carotenoids and Free Radicals in Human Skin

被引：55
|
作者：
Lademann, J. [1 ]
Schanzer, S. [1 ]
Meinke, M. [1 ]
Sterry, W. [1 ]
Darvin, M. E. [1 ]
机构：
[1] Charite Univ Med Berlin, Dept Dermatol, Ctr Expt & Appl Cutaneous Physiol CCP, DE-10117 Berlin, Germany
来源：
SKIN PHARMACOLOGY AND PHYSIOLOGY | 2011年 / 24卷 / 05期
关键词：
Antioxidants; Raman spectroscopy; Electron paramagnetic resonance spectroscopy; Antiaging; Kinetics; RESONANCE RAMAN-SPECTROSCOPY; BETA-CAROTENE; OXIDATIVE STRESS; IR RADIATION; LYCOPENE CONCENTRATIONS; ANTIOXIDANT SUBSTANCES; OXYGEN RADICALS; UV-RADIATION; NITRIC-OXIDE; ULTRAVIOLET;
D O I：
10.1159/000326074
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Environmental factors like air pollutants, radiation of the sun and stress factors such as illness, smoking, or alcohol abuse produce free radicals in the human tissue as well as in the skin. Free radicals serve as the main cause for premature skin aging. Additionally, they also contribute towards immunosuppression and the formation of skin diseases including cancer. The human organism has developed a protection system against the destructive action of free radicals by means of the antioxidant network. In the present study, the interaction of free radicals and carotenoid antioxidants in the human skin under in vivo conditions was investigated and summarized. The measurement of carotenoids in human skin was performed in vivo using resonance Raman spectroscopy. Copyright (C) 2011 S. Karger AG, Basel
引用
收藏
页码：238 / 244
页数：7
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