Stability of cardiac troponins and CK-MB mass isoenzyme

被引：3

作者：

Price, A ^{[1
]}

Burgin, C ^{[1
]}

Cruise, M ^{[1
]}

机构：

[1] No Gen Hosp NHS Trust, Dept Clin Chem, Sheffield S5 7AU, S Yorkshire, England

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2000年 / 38卷 / 11期

关键词：

stability; troponins; CK-MB; cardiac markers;

D O I：

10.1515/CCLM.2000.177

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The stability of an analyte can have an important influence on its diagnostic performance and therefore should be documented before an analyte is introduced into routine practice. The stability of creatine kinase MB isoenzyme (CK-MB). troponin I and troponin T was studied by incubating samples at temperatures between 26 degrees C and 39 degrees C for periods up to 5400 min. Arrhenius plots were made which showed that all three proteins demonstrated a rapid decrease in stability between 15 degrees C and 20 degrees C. The activation energies for CKMB, troponin I and troponin T were 7.7, 6.34 and 6.34 cal/mol, respectively.

引用

页码：1159 / 1160

页数：2

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