Transport across liquid membranes containing vitamin A (retinol acetate)

被引：3
|
作者：
Nagappa, AN [1 ]
Kole, PL
Pandi, PV
Zeeyauddin, K
Patil, RT
Shanmukha, I
机构：
[1] Birla Inst Technol & Sci, Pharm Grp, Pilani 333031, Rajasthan, India
[2] SCS Coll Pharm, Dept Pharmacol, Karnataka 583131, India
来源：
JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2004年 / 271卷 / 02期
关键词：
vitamin A; liquid membrane; surface activity; membrane transport; Kesting's hypothesis;
D O I：
10.1016/j.jcis.2003.12.014
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The role of the surface activity of vitamin A has been studied in the light of the liquid membrane hypothesis of drug action. Transport of relevant amino acids such as serine, threonine, arginine, and histidine and various ions such as calcium, sodium, and potassium in the presence of liquid membranes generated by vitamin A has been studied. The data on the modifications in the permeability of relevant amino acids and ions indicate that the liquid membranes generated by vitamin A may also play a significant role in its physiological action. (C) 2004 Elsevier Inc. All rights reserved.
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页码：416 / 418
页数：3
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