机构:
Univ Calif Los Angeles, Howard Hughes Med Inst, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Biol Chem, Los Angeles, CA 90095 USAUniv Calif Los Angeles, Howard Hughes Med Inst, Los Angeles, CA 90095 USA
De Robertis, E. M.
[1
,2
]
机构:
[1] Univ Calif Los Angeles, Howard Hughes Med Inst, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Biol Chem, Los Angeles, CA 90095 USA
Most animals evolved from a common ancestor, Urbilateria, which already had in place the developmental genetic networks for shaping body plans. Comparative genomics has revealed rather unexpectedly that many of the genes present in bilaterian animal ancestors were lost by individual phyla during evolution. Reconstruction of the archetypal developmental genomic tool-kit present in Urbilateria will help to elucidate the contribution of gene loss and developmental constraints to the evolution of animal body plans.