Cerebral amyloid angiopathy

被引：0

作者：

Block, F. ^{[1
]}

机构：

[1] HELIOS Kliniken Schwerin, Neurol Klin, D-19049 Schwerin, Germany

来源：

NERVENARZT | 2011年 / 82卷 / 02期

关键词：

Cerebral amyloid angiopathy; Risk factors; Apolipoprotein E; Intracerebral hemorrhage; Cerebral imaging; INTRACEREBRAL HEMORRHAGE; MICROBLEEDS; RISK;

D O I：

10.1007/s00115-010-3035-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Cerebral amyloid angiopathy (CAA) is defined by the accumulation of beta-amyloid in the walls of cortical arteries. The risk factors of CAA include advanced age and the presence of certain alleles of apolipoprotein E. CAA mostly remains asymptomatic, but the classical manifestation is intracerebral hemorrhage. A definite diagnosis can only be made on the basis of histopathological examination. Detection of lobar hemorrhages and lobar microhemorrhages in imaging investigations support the diagnosis of CAA as long as other causes can be excluded.

引用

页码：202 / 206

页数：5

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