Synthesis of multifunctional Fe3O4 core/hydroxyapatite shell nanocomposites by biomineralization

被引：36
|
作者：
Huang, Chi [1 ]
Zhou, Yangbo [2 ]
Tang, Zhaomin [2 ]
Guo, Xing [2 ]
Qian, Zhiyong [3 ]
Zhou, Shaobing [1 ,2 ]
机构：
[1] SW Jiaotong Univ, Sch Mat Sci & Engn, Key Lab Adv Technol Mat, Minist Educ, Chengdu 610031, Peoples R China
[2] SW Jiaotong Univ, Sch Life Sci & Engn, Chengdu 610031, Sichuan, Peoples R China
[3] Sichuan Univ, W China Med Sch, W China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China
来源：
DALTON TRANSACTIONS | 2011年 / 40卷 / 18期
基金：
中国国家自然科学基金;
关键词：
IRON-OXIDE NANOPARTICLES; MAGNETIC NANOPARTICLES; HYDROXYAPATITE; DELIVERY; SPHERES;
D O I：
10.1039/c0dt01824d
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Superparamagnetic nanoparticles with surface functional groups (-OH, -COOH and -NH2) were modified by in situ deposition of hydroxyapatite (HA) on the materials' surface through the biomineralization process to form Fe3O4 core/hydroxyapatite shell nanocomposites. They possess potential applications as targeted carriers for antitumor drugs and as bone tissue engineering scaffolds by integrating multiple functions into a single nanosystem.
引用
收藏
页码：5026 / 5031
页数：6
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