New insights into the control of cell growth; The role of the Axl family

被引：50

作者：

Crosier, KE

Crosier, PS

机构：

[1] Department of Molecular Medicine, School of Medicine, University of Auckland

[2] Department of Molecular Medicine, School of Medicine, University of Auckland, Auckland

来源：

PATHOLOGY | 1997年 / 29卷 / 02期

关键词：

receptor tyrosine kinase subfamily; growth-arrest-specific gene 6; tumorigenesis;

D O I：

10.1080/00313029700169744

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Axl, Dtk and Mer are recently described receptors that constitute a new receptor tyrosine kinase subfamily. They bind the vitamin K-dependent protein growth-arrest-specific gene 6 (Gas6) that is structurally related to the anticoagulation factor protein S. Studies suggest a role for these receptors in developmental processes, in the function of the hematopoietic and nervous systems and in tumorigenesis.

引用

页码：131 / 135

页数：5

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