Treatment Outcome of Multidrug-Resistant Mycobacterium tuberculosis in Nepal

被引：8

作者：

Kakchapati, Sampurna

Gyawali, Badri Nath ^{[2
]}

Jha, Rakesh Kumar ^{[3
]}

Choonpradub, Chamnein ^{[1
]}

机构：

[1] Prince Songkla Univ, Dept Math & Comp Sci, Fac Sci & Technol, Muang 94000, Thailand

[2] Natl TB Ctr, Kathmandu, Nepal

[3] Wuhan Univ, Wuhan 430072, Peoples R China

来源：

ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH | 2012年 / 24卷 / 04期

关键词：

multidrug-resistant TB; MDR-TB; treatment outcome; sputum smear conversion; culture conversion; Kaplan-Meier curves; Cox proportional hazards; Nepal;

D O I：

10.1177/1010539511408067

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The purpose of this study was to examine factors associated with treatment outcome of multidrug-resistant tuberculosis (MDR-TB) cases in Nepal. A retrospective analysis of MDR-TB cases by demographic determinants and treatment was conducted. A total of 494 MDR-TB cases were registered from 2005 to 2008, with data obtained from the National Tuberculosis Center. Chi-squared tests were used to assess statistically the association between smear and culture conversion and treatment outcome. Determinants were analyzed with the use of Kaplan Meier curves and Cox proportional hazards models to generate estimates of the associations with the time to treatment outcome. Sputum conversion status and culture conversion status were positively associated with treatment outcome for MDR-TB. In a multiple Cox proportional hazards regression model, no determinants were found to be associated with time to cure.

引用

页码：631 / 640

页数：10

共 50 条

[21] Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants
Ward, HA
Marciniuk, DD
Hoeppner, VH
Jones, W
[J]. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 2005, 9 (02) : 164 - 169
[22] Treatment and outcome analysis of 205 patients with multidrug-resistant tuberculosis
Chan, ED
Laurel, V
Strand, MJ
Chan, JF
Huynh, MLN
Goble, M
Iseman, MD
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 169 (10) : 1103 - 1109
[23] MULTIDRUG-RESISTANT TUBERCULOSIS TREATMENT OUTCOME: TERTIARY CENTER EXPERIENCE
SSS, Aflah
Ismail, Rosmadi
Abu Bakar, Zamzurina
Muttalif, Abdul Razak Abdul
[J]. RESPIROLOGY, 2017, 22 : 63 - 63
[24] Phenotypically occult multidrug-resistant Mycobacterium tuberculosis: dilemmas in diagnosis and treatment
Ho, Jennifer
Jelfs, Peter
Sintchencko, Vitali
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2013, 68 (12) : 2915 - 2920
[25] The pncA gene mutations of Mycobacterium tuberculosis in multidrug-resistant tuberculosis
Mahmood, Nasir
Bhatti, Sadia
Abbas, Shahzada Nadeem
Shahid, Saman
Nasir, Sarah Bushra
[J]. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2022, 69 (05) : 2195 - 2204
[26] Features of the treatment outcome of patients with multidrug-resistant tuberculosis and Beijing lineage 2 of Mycobacterium tuberculosis in Kharkiv region, Ukraine
Butov, Dmytro
Butova, Tetiana
Rudova, Natalia
Sapelnik, Nadiya
Borysova, Olena
Solodiankin, Oleksii
[J]. EUROPEAN RESPIRATORY JOURNAL, 2023, 62
[27] Double infection with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis
Niemann, S
Richter, E
Rüsch-Gerdes, S
Schlaak, M
Greinert, U
[J]. EMERGING INFECTIOUS DISEASES, 2000, 6 (05) : 548 - 551
[28] Multidrug-resistant Mycobacterium tuberculosis transmission in Shandong, China
Li, Yingying
Li, Yifan
Wang, Tingting
Li, Yameng
Tao, Ningning
Kong, Xianglong
Zhang, Yuzhen
Han, Qilin
Liu, Yao
Li, Huaichen
[J]. MEDICINE, 2024, 103 (12)
[29] Transmission of multidrug-resistant Mycobacterium tuberculosis is reality in Switzerland
Niederer-Loher, Anita
Kahlert, Christian
Barben, Juerg
Deggim, Vanessa
Zellweger, Jean-Pierre
[J]. JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, 2012, 7 (04) : 159 - 160
[30] Clusters of Multidrug-Resistant Mycobacterium tuberculosis Cases, Europe
Devaux, Isabelle
Kremer, Kristin
Heersma, Herre
Van Socilingen, Dick
[J]. EMERGING INFECTIOUS DISEASES, 2009, 15 (07) : 1052 - 1060

← 1 2 3 4 5 →