Phase lb study of LEE011 and BYL719 in combination with letrozole in estrogen receptor-positive, HER2-negative breast cancer (ER+, HER2-BC).

被引:4
|
作者
Munster, Pamela N.
Hamilton, Erika Paige
Franklin, Catherine
Bhansali, Suraj
Wan, Kitty
Hewes, Becker
Juric, Dejan
机构
[1] UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA
[2] Tennessee Oncol, Sarah Cannon Res Inst, Nashville, TN USA
[3] Novartis Inst Biomed Res, Cambridge, MA USA
[4] Novartis Pharmaceut, E Hanover, NJ USA
[5] Novartis Pharma AG, Basel, Switzerland
[6] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Ctr Canc, Boston, MA USA
关键词
D O I
10.1200/jco.2014.32.15_suppl.533
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
533
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Imlunestrant monotherapy and in combination with abemaciclib, with or without an aromatase inhibitor, in estrogen receptor-positive (ER+), HER2-negative (HER2-) advanced breast cancer (aBC): updated results from the EMBER study
    Jhaveri, Komal
    Lim, Elgene
    Jeselsohn, Rinath
    Ma, Cynthia
    Hamilton, Erika
    Osborne, Cynthia
    Bhave, Manali
    Kaufman, Peter
    Beck, J. Thaddeus
    Manso, Luis
    Parajuli, Ritesh
    Wang, Hwei-Chung
    Tao, Jessica
    Dhakal, Ajay
    Pierga, Jean-Yves
    Lu, Yen-Shen
    Larson, Tim
    Gilarranz, Yolanda Jerez
    Ismail-Khan, Roohi
    Bacchion, Francesca
    Karacsonyi, Claudia
    Li, Yujia
    Estrem, Shawn T.
    Nguyen, Bastien
    Beeram, Muralidhar
    CANCER RESEARCH, 2024, 84 (09)
  • [22] Immunotherapy for hormone receptor-positive HER2-negative breast cancer
    Cardoso, Fatima
    Hirshfield, Kim M.
    Kraynyak, Kimberly A.
    Tryfonidis, Konstantinos
    Bardia, Aditya
    NPJ BREAST CANCER, 2024, 10 (01)
  • [23] Palbociclib and letrozole for ER-positive, HER2-negative advanced breast cancer
    Abraham, Jame
    Mechcatie, Elizabeth
    JOURNAL OF COMMUNITY AND SUPPORTIVE ONCOLOGY, 2015, 13 (03): : 83 - 86
  • [24] The natural history of untreated estrogen receptor-positive, Her2-negative invasive breast cancer
    Kristin E. Rojas
    Donna-Marie Manasseh
    Mary Rojas
    Andrea Mattocks
    Leah Portnow
    Sarah Kantharia
    Natalie Zelenko
    Christina Giuliano
    Patrick I. Borgen
    Breast Cancer Research and Treatment, 2020, 182 : 79 - 83
  • [25] The Evolving Use of SERDs in Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer
    Jeselsohn, Rinath M.
    CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY, 2021, 19 (07) : 428 - 431
  • [26] Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer
    Nederlof, I
    Hajizadeh, S.
    Sobhani, F.
    Raza, S. E. A.
    AbdulJabbar, K.
    Harkes, R.
    van de Vijver, M. J.
    Salgado, R.
    Desmedt, C.
    Kok, M.
    Yuan, Y.
    Horlings, H. M.
    NPJ BREAST CANCER, 2022, 8 (01)
  • [27] A phase 1b/2 dose escalation and expansion study of OP-1250 in combination with ribociclib or alpelisib in patients with advanced and/or metastatic estrogen receptor-positive (ER+)/HER2-negative (HER2-) breast cancer
    Borges, Virginia F.
    Chan, Arlene
    Lin, Nancy U.
    Tonda, Margaret Eleanor
    Shilkrut, Mark
    Alemany, Carlos A.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [28] Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer
    I. Nederlof
    S. Hajizadeh
    F. Sobhani
    S. E. A. Raza
    K. AbdulJabbar
    R. Harkes
    M. J. van de Vijver
    R. Salgado
    C. Desmedt
    M. Kok
    Y. Yuan
    H. M. Horlings
    npj Breast Cancer, 8
  • [29] Adjuvant endocrine treatment for estrogen receptor (ER)-positive/HER2-negative breast cancer
    Kubo, Makoto
    CHINESE CLINICAL ONCOLOGY, 2020, 9 (03)
  • [30] evERA Breast Cancer (BC): Phase III study of giredestrant plus everolimus vs exemestane plus everolimus in patients (pts) with estrogen receptor-positive, HER2-negative locally advanced or metastatic BC (ER+, HER2-LA/mBC)
    Mayer, Erica L.
    Tolaney, Sara M.
    Brufsky, Adam
    Gradishar, William John
    Jhaveri, Komal L.
    Martin, Miguel
    Moscetti, Luca
    Schneeweiss, Andreas
    Vidal, Gregory A.
    Cortazar, Patricia
    Feldman, Merilin
    Day, Bann-mo
    Rugo, Hope S.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)