Transgenic Mouse Models and Prion Strains

被引：20
|
作者：
Telling, Glenn C. [1 ,2 ,3 ]
机构：
[1] Univ Kentucky, Med Ctr, Sanders Brown Ctr Aging, Lexington, KY 40506 USA
[2] Univ Kentucky, Med Ctr, Dept Microbiol Immunol & Mol Genet, Lexington, KY 40506 USA
[3] Univ Kentucky, Med Ctr, Dept Neurol, Lexington, KY 40506 USA
来源：
PRION PROTEINS | 2011年 / 305卷
关键词：
Quasi-species; Species barriers; Strains; Transgenic models; CHRONIC WASTING DISEASE; CREUTZFELDT-JAKOB-DISEASE; TRANSMISSIBLE MINK ENCEPHALOPATHY; CERVUS-ELAPHUS-NELSONI; MICE EXPRESSING HUMAN; NATURAL SHEEP SCRAPIE; WHITE-TAILED DEER; SPONGIFORM ENCEPHALOPATHY; VARIANT CJD; EXPERIMENTAL-INFECTION;
D O I：
10.1007/128_2011_166
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Here we review the known strain profiles of various prion diseases of animals and humans, and how transgenic mouse models are being used to elucidate basic molecular mechanisms of prion propagation and strain variation and for assessing the zoonotic potential of various animal prion strains.
引用
收藏
页码：79 / 99
页数：21
相关论文
共 50 条
  • [41] Transgenic mouse models of dopamine deficiency
    Chen, L
    Zhuang, XX
    [J]. ANNALS OF NEUROLOGY, 2003, 54 : S91 - S102
  • [42] Transgenic mouse models for gonadal tumorigenesis
    Rahman, NA
    Rilianawati, KK
    Paukku, T
    Mikola, M
    Markkula, M
    Hämäläinen, T
    Huhtaniemi, IT
    [J]. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1998, 145 (1-2) : 167 - 174
  • [43] TRANSGENIC MOUSE MODELS OF VASOPRESSIN EXPRESSION
    GRANT, FD
    REVENTOS, J
    KAWABATA, S
    MILLER, M
    GORDON, JW
    MAJZOUB, JA
    [J]. HYPERTENSION, 1993, 22 (04) : 640 - 645
  • [44] Drug testing in transgenic mouse models
    Varticovski, L.
    Hollingshead, M. G.
    Anver, M. R.
    Robles, A. I.
    Barrett, J.
    [J]. CHEMICO-BIOLOGICAL INTERACTIONS, 2006, 161 (03) : 226 - 226
  • [45] Transgenic Mouse Models in Cancer Research
    Tratar, Ursa Lampreht
    Horvat, Simon
    Cemazar, Maja
    [J]. FRONTIERS IN ONCOLOGY, 2018, 8
  • [46] Transgenic mouse models in addiction research
    Robledo, P.
    Martin-Garcia, E.
    Plaza-Zavala, A.
    Berrendero, F.
    Maldonado, R.
    [J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2010, 20 : S200 - S201
  • [47] Transgenic mouse models of multiple sclerosis
    Tanja Scheikl
    Béatrice Pignolet
    Lennart T. Mars
    Roland S. Liblau
    [J]. Cellular and Molecular Life Sciences, 2010, 67 : 4011 - 4034
  • [48] Transgenic mouse models of multiple sclerosis
    Scheikl, Tanja
    Pignolet, Beatrice
    Mars, Lennart T.
    Liblau, Roland S.
    [J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 2010, 67 (23) : 4011 - 4034
  • [49] Transgenic mouse models of breast cancer
    Amundadottir, LT
    Merlino, G
    Dickson, RB
    [J]. BREAST CANCER RESEARCH AND TREATMENT, 1996, 39 (01) : 119 - 135
  • [50] Transgenic mouse models of breast cancer
    Regua, Angelina T.
    Arrigo, Austin
    Doheny, Daniel
    Wong, Grace L.
    Lo, Hui-Wen
    [J]. CANCER LETTERS, 2021, 516 : 73 - 83
12345