A study of increased levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) in the cerebrospinal fluid of patients with multiple sclerosis and systemic lupus erythematosus

被引：11
|
作者：
Baraczka, K
Pozsonyi, T
Szongoth, M
Nékám, K
Megyeri, A
Balogh, Z
Jakab, L
机构：
[1] Natl Inst Rheumatol & Physiotherapy, Budapest, Hungary
[2] Dept Neurol, Budapest, Hungary
[3] Semmelweis Med Sch, Clin Internal Med 3, Budapest, Hungary
来源：
ACTA NEUROLOGICA SCANDINAVICA | 1999年 / 99卷 / 02期
关键词：
multiple sclerosis; systemic lupus erythematosus; cerebrospinal fluid; soluble vascular cell adhesion molecules;
D O I：
10.1111/j.1600-0404.1999.tb00664.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The concentration of soluble vascular cell adhesion molecules (sVCAM-1) of serum and cerebrospinal fluid (CSF) was measured in clinically selected multiple sclerosis (MS) and systemic lupus erythematosus (SLE) patients, using an ELISA assay. The mean sVCAM-1 concentration in the serum of SLE patients was higher than normal. The mean CSF sVCAM-1 concentration was increased in the MS as in the SLE group. On analysis, the data suggests that there are some similarities in the immunological effects of these two different diseases of the central nervous system. A longitudinal analysis of the CSF is requested.
引用
收藏
页码：95 / 99
页数：5
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