Insulin action and insulin resistance: Diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system

被引：121
|
作者：
Hunter, SJ
Garvey, WT [1 ]
机构：
[1] Med Univ S Carolina, Dept Med, Charleston, SC 29425 USA
[2] Ralph H Johnson Vet Affairs Med Ctr, Charleston, SC USA
来源：
AMERICAN JOURNAL OF MEDICINE | 1998年 / 105卷 / 04期
关键词：
D O I：
10.1016/S0002-9343(98)00300-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Insulin resistance is a primary abnormality in the evolution of type 2 diabetes and is associated with Syndrome X, a cluster of risk factors predisposing to cardiovascular disease. In the polycystic ovary syndrome, insulin resistance may lead to hyperandrogenism; troglitazone, an insulin sensitizer, corrects abnormalities in the pituitary/gonadal axis in these patients.
引用
收藏
页码：331 / 345
页数：15
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