Ectoine Biosynthesis in Mycobacterium smegmatis

被引：36

作者：

Ofer, Naomi ^{[1
]}

Wishkautzan, Marina ^{[1
,2
]}

Meijler, Michael M. ^{[2
,3
]}

Wang, Ying ^{[4
]}

Speer, Alexander ^{[4
]}

Niederweis, Michael ^{[4
]}

Gur, Eyal ^{[1
,2
]}

机构：

[1] Ben Gurion Univ Negev, Dept Life Sci, IL-84105 Beer Sheva, Israel

[2] Ben Gurion Univ Negev, Natl Inst Biotecnol Negev, IL-84105 Beer Sheva, Israel

[3] Ben Gurion Univ Negev, Dept Chem, Beer Sheva, Israel

[4] Univ Alabama Birmingham, Dept Microbiol, Birmingham, AL 35294 USA

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2012年 / 78卷 / 20期

关键词：

COMPATIBLE SOLUTE ECTOINE; SALT-SENSITIVE MUTANTS; INHIBIT AGGREGATION; HALOMONAS-ELONGATA; HYDROXYECTOINE; OSMOADAPTATION; NEUROTOXICITY; STABILIZATION; BACTERIA; ARCHAEA;

D O I：

10.1128/AEM.01318-12

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Mycobacterium smegmatis is a commonly used mycobacterial model system. Here, we show that M. smegmatis protects itself against elevated salinity by synthesizing ectoine and hydroxyectoine and characterize the phenotype of a nonproducing mutant. This is the first analysis of M. smegmatis halotolerance and of the molecular mechanism that supports it.

引用

页码：7483 / 7486

页数：4

共 50 条

[41] Overexpression of Mycobacterium tuberculosis manB, a phosphomannomutase that increases phosphatidylinositol mannoside biosynthesis in Mycobacterium smegmatis and mycobacterial association with human macrophages
McCarthy, TR
Torrelles, JB
MacFarlane, AS
Katawczik, M
Kutzbach, B
DesJardin, LE
Clegg, S
Goldberg, JB
Schlesinger, LS
MOLECULAR MICROBIOLOGY, 2005, 58 (03) : 774 - 790
[42] Cholesterol uptake in Mycobacterium smegmatis
Garcia-Fernandez, J.
Medrano, F. J.
Galan, B.
Garcia, J. L.
FEBS JOURNAL, 2012, 279 : 261 - 261
[43] Accumulation of rifampicin by Mycobacterium aurum, Mycobacterium smegmatis and Mycobacterium tuberculosis
Piddock, LJV
Williams, KJ
Ricci, V
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 (02) : 159 - 165
[44] TRYPTOPHAN SYNTHETASE IN MYCOBACTERIUM SMEGMATIS
RATLEDGE, C
WINDER, FG
BIOCHEMICAL JOURNAL, 1961, 80 (02) : P20 - &
[45] The respiratory chain of Mycobacterium smegmatis
Adelroth, Pia
Vilhjalmsdottir, Johanna
Janczak, Mateusz
Stah, Olga
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2024, 1865 : 16 - 17
[46] Cholesterol metabolism in Mycobacterium smegmatis
Uhia, Iria
Galan, Beatriz
Kendall, Sharon L.
Stoker, Neil G.
Garcia, Jose L.
ENVIRONMENTAL MICROBIOLOGY REPORTS, 2012, 4 (02): : 168 - 182
[47] Transcriptome Landscape of Mycobacterium smegmatis
Li, Xinfeng
Mei, Han
Chen, Fang
Tang, Qing
Yu, Zhaoqing
Cao, Xiaojian
Andongma, Binda T.
Chou, Shan-Ho
He, Jin
FRONTIERS IN MICROBIOLOGY, 2017, 8
[48] CONJUGATION IN MYCOBACTERIUM-SMEGMATIS
KONICEK, J
FOLIA MICROBIOLOGICA, 1975, 20 (01) : 64 - 64
[49] Photodynamic inactivation with Mycobacterium smegmatis
Feese, Elke
Ghiladi, Reza A.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
[50] TRANSDUCTION IN MYCOBACTERIUM-SMEGMATIS
RAJ, CVS
RAMAKRIS.T
NATURE, 1970, 228 (5268) : 280 - &

← 1 2 3 4 5 →