Characterizing the mechanism and the clinical relevance of the synthetic lethal interaction between STAT3 inhibition and HER2 overexpression in breast cancers

被引：1

作者：

Barrueco, Ruth Rodriguez ^{[1
]}

Yu, Jiyang ^{[1
]}

Alvarez, Mariano ^{[1
]}

Castro, Veronica ^{[1
]}

Marshall, Netonia ^{[1
]}

Su, Ruoxi ^{[1
]}

Castro, Laura ^{[1
]}

Maurer, Matthew ^{[1
]}

Califano, Andrea ^{[1
]}

Silva, Jose M. ^{[1
]}

机构：

[1] Columbia Univ, New York, NY USA

来源：

CANCER RESEARCH | 2014年 / 74卷 / 19期

关键词：

D O I：

10.1158/1538-7445.AM2014-2761

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

2761

引用

页数：2

共 46 条

[1] Characterizing the mechanism and the clinical relevance of the synthetic lethal interaction between STAT3 inhibition and HER2 overexpression in breast cancers
Rodriguez-Barrueco, Ruth
Yu, Jiyang
Alvarez, Mariano
Castro, Veronica
Villagrasa, Patricia
Marshall, Netonia
Sun, Ruoxi
Castro, Laura
Califano, Andrea
MOLECULAR CANCER THERAPEUTICS, 2013, 12 (05)
[2] Synthetic lethal strategies in ER/HER2 negative breast cancers
Tutt, A.
EJC SUPPLEMENTS, 2010, 8 (03): : 185 - 185
[3] Inhibition of the STAT3/Fanconi anemia axis is synthetic lethal with PARP inhibition in breast cancer
Rouault, Celia D.
Bansard, Lucile
Martinez-Balsalobre, Elena
Bonnet, Caroline
Wicinski, Julien
Lin, Shuheng
Colombeau, Ludovic
Debieu, Sylvain
Pinna, Guillaume
Vandamme, Marie
Machu, Margot
Rosnet, Olivier
Chevrier, Veronique
Popovici, Cornel
Sobol, Hagay
Castellano, Remy
Pasquier, Eddy
Guasch, Geraldine
Rodriguez, Raphael
Pannequin, Julie
Pascussi, Jean-Marc
Lachaud, Christophe
Charafe-Jauffret, Emmanuelle
Ginestier, Christophe
NATURE COMMUNICATIONS, 2025, 16 (01)
[4] Her2 amplifies the opposing roles of STAT3 and STAT5 in breast cancer.
Walker, SR
Frank, DA
BREAST CANCER RESEARCH AND TREATMENT, 2004, 88 : S215 - S215
[5] Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers
Yi Ding
Chang Gong
De Huang
Rui Chen
Pinpin Sui
Kevin H. Lin
Gehao Liang
Lifeng Yuan
Handan Xiang
Junying Chen
Tao Yin
Peter B. Alexander
Qian-Fei Wang
Er-Wei Song
Qi-Jing Li
Kris C. Wood
Xiao-Fan Wang
Nature Communications, 9
[6] Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers
Ding, Yi
Gong, Chang
Huang, De
Chen, Rui
Sui, Pinpin
Lin, Kevin H.
Liang, Gehao
Yuan, Lifeng
Xiang, Handan
Chen, Junying
Yin, Tao
Alexander, Peter B.
Wang, Qian-Fei
Song, Er-Wei
Li, Qi-Jing
Wood, Kris C.
Wang, Xiao-Fan
NATURE COMMUNICATIONS, 2018, 9
[7] Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells
Lee, Hsueh-Te
Xue, Jianfei
Chou, Ping-Chieh
Zhou, Aidong
Yang, Phillip
Conrad, Charles A.
Aldape, Kenneth D.
Priebe, Waldemar
Patterson, Cam
Sawaya, Raymond
Xie, Keping
Huang, Suyun
ONCOTARGET, 2015, 6 (12) : 10016 - 10029
[8] Constitutively activated STAT3 is predictive for trastuzumab resistance in primary HER2 positive breast cancer
Sonnenblick, A.
Brohee, S.
Salgado, R. F.
Van den Eynden, G.
Neven, P.
Loibl, S.
Denkert, C.
Joensuu, H.
Piccart, M.
Sotiriou, C.
ANNALS OF ONCOLOGY, 2015, 26
[9] A triad of Brk, HER2 and STAT3 in regulating epithelial and mesenchymal transition and survival of breast cancer cells
Ai, Midan
CANCER RESEARCH, 2012, 72
[10] Clinical Relevance of HER2 Overexpression/Amplification in Patients With Small Tumor Size and Node-Negative Breast Cancer
Curigliano, Giuseppe
Viale, Giuseppe
Bagnardi, Vincenzo
Fumagalli, Luca
Locatelli, Marzia
Rotmensz, Nicole
Ghisini, Raffaella
Colleoni, Marco
Munzone, Elisabetta
Veronesi, Paolo
Zurrida, Stefano
Nole, Franco
Goldhirsch, Aron
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (34) : 5693 - 5699

← 1 2 3 4 5 →