Constituents from leaves of Apocynum venetum L.

被引：62

作者：

Kamata, Kazuaki ^{[1
]}

Seo, Shujiro ^{[1
]}

Nakajima, Jun-Ichiro ^{[1
]}

机构：

[1] Tokiwa Phytochem Co Ltd, Chiba 2850801, Japan

来源：

JOURNAL OF NATURAL MEDICINES | 2008年 / 62卷 / 02期

关键词：

Apocynum venetum; apocynaceae; LC-MS; NMR; malonated flavonol glycoside; antioxidant;

D O I：

10.1007/s11418-007-0202-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An analysis using HPLC-MS revealed that an extract from dried leaves of Apocynum venetum L. contained more than 15 kinds of phenolic constituents. Two malonated flavonol glycosides were further isolated, and their structures were determined to be quercetin 3-O-(6''-O-malonyl)-beta-D-glucoside (1) and quercetin 3-O-(6''-O-malonyl)-beta-D-galactoside (2) by NMR spectroscopic analysis. This is the first report describing the isolation of these malonated flavonol glycosides from A. venetum L. Both glycosides showed strong scavenging activity against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical.

引用

页码：160 / 163

页数：4

共 50 条

[21] PHYSIOLOGICAL RESPONSE OF APOCYNUM VENETUM L. SEEDLINGS UNDER OSMOTIC STRESS
Zhao, Hua
Dai, Huiping
[J]. BANGLADESH JOURNAL OF BOTANY, 2015, 44 (04): : 551 - 556
[22] Study on active compounds of Apocynum venetum L
Zhong, You-quan
Xu, Xiang-qun
Yang, Jie
Cheng, Lin
[J]. FRONTIERS OF MANUFACTURING AND DESIGN SCIENCE IV, PTS 1-5, 2014, 496-500 : 163 - 166
[23] Optimization of Explants and Hormone Combinations for Callus Induction of Apocynum venetum L.
Xiaochen LIU
Junmai CAO
Guoqi LI
Yanyun CHEN
[J]. Medicinal Plant, 2013, (04) : 74 - 75
[24] Anxiolytic activity of Apocynum venetum L. and its proposed mechanism of action
Grundmann, O.
Nakajima, J.
Butterweck, V
[J]. PLANTA MEDICA, 2008, 74 (03) : 315 - 315
[25] Study on Biological Materials with Flavonoid active compounds of Apocynum venetum L.
Zhong, Youquan
Liu, Yilu
Zhang, Wugang
Yang, Jie
Cheng, Lin
[J]. MATERIALS SCIENCE, ENVIRONMENT PROTECTION AND APPLIED RESEARCH, 2014, 908 : 133 - +
[26] The Antibacterial Activity of the Extracts of Apocynum Venetum and Apocynum Venetum Fiber
Wang, Huijuan
Chen, Hao
Han, Guangting
[J]. FUNDAMENTAL OF CHEMICAL ENGINEERING, PTS 1-3, 2011, 233-235 : 2328 - +
[27] Antidepressant effects of Apocynum venetum leaves in a forced swimming test
Butterweck, V
Nishibe, S
Sasaki, T
Uchida, M
[J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2001, 24 (07) : 848 - 851
[28] Effects of aqueous extracts of Apocynum venetum leaves on hypercholesterolaemic rats
Kim, DW
Yokozawa, T
Hattori, M
Kadota, S
Namba, T
[J]. PHYTOTHERAPY RESEARCH, 1998, 12 (01) : 46 - 48
[29] Comparison of the constituents of Apocynum venetum and acidified Apocynum venetum by liquid chromatography–UV diode array detection–electrospray ionisation mass spectrometry
Yuchi Zhang
Chunming Liu
Yanjuan Qi
Zhengkun Zhang
[J]. Medicinal Chemistry Research, 2012, 21 : 1684 - 1691
[30] Cardiotonic effect of Apocynum venetum L. extracts on isolated guinea pig atrium
Kaoru Irie
Takahiro Sato
Ippei Tanaka
Jun-ichiro Nakajima
Maiko Kawaguchi
Toshiyuki Himi
[J]. Journal of Natural Medicines, 2009, 63 : 111 - 116

← 1 2 3 4 5 →