Human Brain Proteome-Wide Association Study of Depression Identified 24 Proteins as Tractable Targets for Further Mechanistic Studies

被引:0
|
作者
Wingo, Thomas S. [1 ]
Liu, Yue [1 ]
Lori, Adriana [2 ]
Gerasimov, Ekaterina S. [1 ]
Duong, Duc M. [1 ]
Dammer, Eric [2 ]
Ressler, Kerry [3 ]
Lah, James [1 ]
Bennett, David [4 ]
Seyfried, Nicholas T. [1 ]
Levey, Allan I. [1 ]
Wingo, Aliza [5 ,6 ]
机构
[1] Emory Univ, Sch Med, Atlanta, GA 30322 USA
[2] Emory Univ, Atlanta, GA 30322 USA
[3] McLean Hosp, 115 Mill St, Belmont, MA 02178 USA
[4] Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
[5] Emory Univ, Atlanta, GA 30322 USA
[6] Atlanta VA, Atlanta, GA USA
关键词
Proteome-Wide Association Study; Depression; Human Brain; Mendelian Randomization;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:S183 / S183
页数:1
相关论文
共 27 条
  • [21] Brain Proteome-Wide Association Study Identifies Candidate Genes that Regulate Protein Abundance Associated with Post-Traumatic Stress Disorder
    Zhang, Zhen
    Meng, Peilin
    Zhang, Huijie
    Jia, Yumeng
    Wen, Yan
    Zhang, Jingxi
    Chen, Yujing
    Li, Chun'e
    Pan, Chuyu
    Cheng, Shiqiang
    Yang, Xuena
    Yao, Yao
    Liu, Li
    Zhang, Feng
    GENES, 2022, 13 (08)
  • [22] Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies
    S I Shyn
    J Shi
    J B Kraft
    J B Potash
    J A Knowles
    M M Weissman
    H A Garriock
    J S Yokoyama
    P J McGrath
    E J Peters
    W A Scheftner
    W Coryell
    W B Lawson
    D Jancic
    P V Gejman
    A R Sanders
    P Holmans
    S L Slager
    D F Levinson
    S P Hamilton
    Molecular Psychiatry, 2011, 16 : 202 - 215
  • [23] Nominating novel proteins for anxiety via integrating human brain proteomes and genome-wide association study
    Jin, Xing
    Dong, Shuangshuang
    Yang, Yang
    Bao, Guangyu
    Ma, Haochuan
    JOURNAL OF AFFECTIVE DISORDERS, 2024, 358 : 129 - 137
  • [24] Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies
    Shyn, S. I.
    Shi, J.
    Kraft, J. B.
    Potash, J. B.
    Knowles, J. A.
    Weissman, M. M.
    Garriock, H. A.
    Yokoyama, J. S.
    McGrath, P. J.
    Peters, E. J.
    Scheftner, W. A.
    Coryell, W.
    Lawson, W. B.
    Jancic, D.
    Gejman, P. V.
    Sanders, A. R.
    Holmans, P.
    Slager, S. L.
    Levinson, D. F.
    Hamilton, S. P.
    MOLECULAR PSYCHIATRY, 2011, 16 (02) : 202 - 215
  • [25] Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits
    Sylvanus Toikumo
    Heng Xu
    Joel Gelernter
    Rachel L. Kember
    Henry R. Kranzler
    Neuropsychopharmacology, 2022, 47 : 2292 - 2299
  • [26] Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits
    Toikumo, Sylvanus
    Xu, Heng
    Gelernter, Joel
    Kember, Rachel L.
    Kranzler, Henry R.
    NEUROPSYCHOPHARMACOLOGY, 2022, 47 (13) : 2292 - 2299
  • [27] A Conserved BDNF, Glutamate- and GABA-Enriched Gene Module Related to Human Depression Identified by Coexpression Meta-Analysis and DNA Variant Genome-Wide Association Studies
    Chang, Lun-Ching
    Jamain, Stephane
    Lin, Chien-Wei
    Rujescu, Dan
    Tseng, George C.
    Sibille, Etienne
    PLOS ONE, 2014, 9 (03):