Human Brain Proteome-Wide Association Study of Depression Identified 24 Proteins as Tractable Targets for Further Mechanistic Studies

被引：0
|
作者：
Wingo, Thomas S. [1 ]
Liu, Yue [1 ]
Lori, Adriana [2 ]
Gerasimov, Ekaterina S. [1 ]
Duong, Duc M. [1 ]
Dammer, Eric [2 ]
Ressler, Kerry [3 ]
Lah, James [1 ]
Bennett, David [4 ]
Seyfried, Nicholas T. [1 ]
Levey, Allan I. [1 ]
Wingo, Aliza [5 ,6 ]
机构：
[1] Emory Univ, Sch Med, Atlanta, GA 30322 USA
[2] Emory Univ, Atlanta, GA 30322 USA
[3] McLean Hosp, 115 Mill St, Belmont, MA 02178 USA
[4] Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
[5] Emory Univ, Atlanta, GA 30322 USA
[6] Atlanta VA, Atlanta, GA USA
来源：
BIOLOGICAL PSYCHIATRY | 2020年 / 87卷 / 09期
关键词：
Proteome-Wide Association Study; Depression; Human Brain; Mendelian Randomization;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页码：S183 / S183
页数：1
相关论文
共 27 条
  • [1] Brain proteome-wide association study implicates novel proteins in depression pathogenesis
    Thomas S. Wingo
    Yue Liu
    Ekaterina S. Gerasimov
    Jake Gockley
    Benjamin A. Logsdon
    Duc M. Duong
    Eric B. Dammer
    Adriana Lori
    Paul J. Kim
    Kerry J. Ressler
    Thomas G. Beach
    Eric M. Reiman
    Michael P. Epstein
    Philip L. De Jager
    James J. Lah
    David A. Bennett
    Nicholas T. Seyfried
    Allan I. Levey
    Aliza P. Wingo
    Nature Neuroscience, 2021, 24 : 810 - 817
  • [2] Brain proteome-wide association study implicates novel proteins in depression pathogenesis
    Wingo, Thomas S.
    Liu, Yue
    Gerasimov, Ekaterina S.
    Gockley, Jake
    Logsdon, Benjamin A.
    Duong, Duc M.
    Dammer, Eric B.
    Lori, Adriana
    Kim, Paul J.
    Ressler, Kerry J.
    Beach, Thomas G.
    Reiman, Eric M.
    Epstein, Michael P.
    De Jager, Philip L.
    Lah, James J.
    Bennett, David A.
    Seyfried, Nicholas T.
    Levey, Allan, I
    Wingo, Aliza P.
    NATURE NEUROSCIENCE, 2021, 24 (06) : 810 - 817
  • [3] Human Brain Proteome-Wide Association Study of Longitudinally Assessed Late-Life Depression
    Wingo, Aliza
    Fan, Wen
    Seyfried, Nicholas
    Duc Duong
    Dammer, Eric
    Bennett, David
    Lah, James
    Levey, Allan
    Wingo, Thomas
    BIOLOGICAL PSYCHIATRY, 2019, 85 (10) : S249 - S249
  • [4] Identification of Human Brain Proteins for Bitter-Sweet Taste Perception: A Joint Proteome-Wide and Transcriptome-Wide Association Study
    Wei, Wenming
    Cheng, Bolun
    He, Dan
    Zhao, Yijing
    Qin, Xiaoyue
    Cai, Qingqing
    Zhang, Na
    Chu, Xiaoge
    Shi, Sirong
    Zhang, Feng
    NUTRIENTS, 2022, 14 (10)
  • [5] Plasma proteome analysis implicates novel proteins as potential therapeutic targets for chronic kidney disease: A proteome-wide association study
    Xiong, Yang
    Wang, Tianhong
    Wang, Wei
    Zhang, Yangchang
    Zhang, Fuxun
    Yuan, Jiuhong
    Qin, Feng
    Wang, Xianding
    HELIYON, 2024, 10 (11)
  • [6] The genetic structure of pain in depression patients: A genome-wide association study and proteome-wide association study
    Zhang, Zhen
    Liu, Li
    Zhang, Huijie
    Li, Chun'e
    Chen, Yujing
    Zhang, Jingxi
    Pan, Chuyu
    Cheng, Shiqiang
    Yang, Xuena
    Meng, Peilin
    Yao, Yao
    Jia, Yumeng
    Wen, Yan
    Zhang, Feng
    JOURNAL OF PSYCHIATRIC RESEARCH, 2022, 156 : 547 - 556
  • [7] A proteome-wide association study identifies putative causal proteins for breast cancer
    Zhao, Tianying
    Xu, Shuai
    Ping, Jie
    Jia, Guochong
    Dou, Yongchao
    Zhang, Bing
    Guo, Xingyi
    Cai, Qiuyin
    Shu, Xiao-Ou
    Zheng, Wei
    Long, Jirong
    CANCER RESEARCH, 2024, 84 (06)
  • [8] Multivariate proteome-wide association study to identify causal proteins for Alzheimer disease
    Fang, Lei
    Xue, Haoran
    Lin, Zhaotong
    Pan, Wei
    AMERICAN JOURNAL OF HUMAN GENETICS, 2025, 112 (02)
  • [9] Integrated analysis of proteome-wide and transcriptome-wide association studies identified novel genes and chemicals for vertigo
    Cheng, Bolun
    Meng, Peilin
    Yang, Xuena
    Cheng, Shiqiang
    Liu, Li
    Jia, Yumeng
    Wen, Yan
    Zhang, Feng
    BRAIN COMMUNICATIONS, 2022, 4 (06)
  • [10] Identification of novel functional brain proteins for treatment-resistant schizophrenia: Based on a proteome-wide association study
    Wei, Wenming
    Zhang, Huijie
    Cheng, Bolun
    Qin, Xiaoyue
    He, Dan
    Zhang, Na
    Zhao, Yijing
    Cai, Qingqing
    Shi, Sirong
    Chu, Xiaoge
    Wen, Yan
    Liu, Huan
    Jia, Yumeng
    Zhang, Feng
    EUROPEAN PSYCHIATRY, 2023, 66 (01)
123