A general method for the direct α-arylation of aldehydes with aryl bromides and chlorides

被引：104
|
作者：
Martin, Ruben [1 ]
Buchwald, Stephen L. [1 ]
机构：
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 38期
关键词：
aldehydes; arylation; homogeneous catalysis; P ligands; palladium;
D O I：
10.1002/anie.200703009
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Wide scope: A catalyst system able to efficiently perform the title reaction is described (see scheme). The high level of activity achieved allows for the synthesis of highly functionalized compounds with a wide variety of substitution patterns under very mild conditions. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：7236 / 7239
页数：4
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