Animal models of psychiatric disorders and their relevance to alcoholism

被引:0
|
作者
Hitzemann, R [1 ]
机构
[1] Oregon Hlth & Sci Univ, Dept Behav Neurosci, Portland, OR 97201 USA
[2] Oregon Hlth & Sci Univ, Vet Affairs Med Ctr, Res Serv, Portland, OR 97201 USA
关键词
animal model; behavioral and mental disorder; AOD (alcohol or other drug) dependence; comorbidity; validity (research methods); reliability (research methods); schizophrenia; emotional and psychiatric depression; fear; anxiety; animal strains;
D O I
暂无
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Animal models are important fools in the study of psychiatric disorders, including alcoholism,(1) because they allow the use of research methods that cannot be used for ethical reasons in humans. Consequently, scientists have developed numerous approaches to evaluate the validity and reliability of animal models for studying human behavior and human disorders. Researchers have developed animal models of schizophrenia, fear and anxiety, depression, and alcoholism, all of which are being used to study the relationship between alcoholism and co-occurring psychiatric disorders. These models may help researchers and clinicians determine how best to treat patients with alcoholism and co-occurring psychiatric disorders.
引用
收藏
页码:149 / 158
页数:10
相关论文
共 50 条
  • [31] Reconsideration of animal models of schizophrenia and other psychiatric disorders with evolutionary perspective
    Lee, Young-A
    Goto, Yukiori
    MEDICAL HYPOTHESES, 2013, 81 (06) : 1120 - 1126
  • [32] Animal Models of Psychiatric Disorders That Reflect Human Copy Number Variation
    Nomura, Jun
    Takumi, Toru
    NEURAL PLASTICITY, 2012, 2012
  • [33] Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders
    Laviola, Giovanni
    Hannan, Anthony J.
    Macri, Simone
    Solinas, Marcello
    Jaber, Mohamed
    NEUROBIOLOGY OF DISEASE, 2008, 31 (02) : 159 - 168
  • [34] Metabolomics in Psychiatric Disorders: What We Learn from Animal Models
    Humer, Elke
    Probst, Thomas
    Pieh, Christoph
    METABOLITES, 2020, 10 (02)
  • [35] Therapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders
    Zhang, ZJ
    LIFE SCIENCES, 2004, 75 (14) : 1659 - 1699
  • [36] Animal Models of Speech and Vocal Communication Deficits Associated With Psychiatric Disorders
    Konopka, Genevieve
    Roberts, Todd F.
    BIOLOGICAL PSYCHIATRY, 2016, 79 (01) : 53 - 61
  • [37] Neuropharmacological Effects of Terpenoids on Preclinical Animal Models of Psychiatric Disorders: A Review
    Mony, Tamanna Jahan
    Elahi, Fazle
    Choi, Ji Woong
    Park, Se Jin
    ANTIOXIDANTS, 2022, 11 (09)
  • [38] EPIGENETICS AND INFLAMMATION IN CHILDHOOD PSYCHIATRIC DISORDERS: EVIDENCE FROM ANIMAL MODELS
    Reiersen, Angela M.
    Mehta, Sunil Q.
    JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2020, 59 (10): : S293 - S294
  • [39] ALCOHOLISM AND PREVALENCE OF MEDICAL AND PSYCHIATRIC-DISORDERS
    MENDELSON, JH
    BABOR, TF
    MELLO, NK
    PRATT, H
    JOURNAL OF STUDIES ON ALCOHOL, 1986, 47 (05): : 361 - 366
  • [40] Animal cruelty and psychiatric disorders
    Gleyzer, R
    Felthous, AR
    Holzer, CE
    JOURNAL OF THE AMERICAN ACADEMY OF PSYCHIATRY AND THE LAW, 2002, 30 (02): : 257 - 265