Synthesis, spectroscopic characterization and antibacterial activity of lanthanide-tetracycline complexes

被引：29

作者：

Karthikeyan, G ^{[1
]}

Mohanraj, K

Elango, KP

Girishkumar, K

机构：

[1] Deemed Univ, Gandhigram Rural Inst, Dept Chem, Gandhigram 624302, India

[2] Cochin Univ Sci & Technol, Dept Appl Chem, Cochin 682022, Kerala, India

来源：

TRANSITION METAL CHEMISTRY | 2004年 / 29卷 / 01期

关键词：

D O I：

10.1023/B:TMCH.0000014490.54611.5a

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of Ln(III)-tetracycline complexes of the type [Ln(TC)Cl-3].2H(2)O [Ln = lanthanum, praseodymium, neodymium, samarium, gadolinium, terbium, dysprosium and yttrium; TC = tetracycline] have been synthesized and characterized by analytical, i.r., electronic, H-1-n.m.r. spectral studies, X-ray diffraction and thermogravimetric analysis. A pentagonal bipyramidal structure has been tentatively proposed for the new complexes. The ligand and the new complexes were tested in vitro to evaluate their activity against the bacteria Escherichia coli and Staphylococcus aureus.

引用

页码：86 / 90

页数：5

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