beta-Blockers have been one of the most widely used and versatile drugs for the past half a century. A new potential for their use as anti-cancer drugs has emerged in the past few years. Various retrospective case control studies have been suggestive that use of beta-blockers before the diagnosis of cancer could have preventive and protective effects against non-small cell lung carcinoma, melanoma, and breast, pancreatic and prostate cancers. Experimental and clinical observations are still inconclusive with some inconsistent findings. However, indications are pointing toward a positive role of some beta-blockers against certain forms of cancers. This mini review is an effort to present the up to date published results of case-control studies and experimental findings.
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Cent Univ, Jamia Millia Islamia, Dept Chem, New Delhi 110025, IndiaCent Univ, Jamia Millia Islamia, Dept Chem, New Delhi 110025, India
Ali, Imran
Lone, Mohammad Nadeem
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Cent Univ, Jamia Millia Islamia, Dept Chem, New Delhi 110025, IndiaCent Univ, Jamia Millia Islamia, Dept Chem, New Delhi 110025, India
Lone, Mohammad Nadeem
Aboul-Enein, Haasan Y.
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Natl Res Ctr, Pharmaceut & Drug Ind Res Div, Pharmaceut & Med Chem Dept, Giza 12622, EgyptCent Univ, Jamia Millia Islamia, Dept Chem, New Delhi 110025, India
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Henry Ford Hosp, Henry Ford Heart & Vasc Inst, Sect Cardiac Electrophysiol, Detroit, MI 48202 USAHenry Ford Hosp, Henry Ford Heart & Vasc Inst, Sect Cardiac Electrophysiol, Detroit, MI 48202 USA
Anh, D
Marine, JE
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Henry Ford Hosp, Henry Ford Heart & Vasc Inst, Sect Cardiac Electrophysiol, Detroit, MI 48202 USAHenry Ford Hosp, Henry Ford Heart & Vasc Inst, Sect Cardiac Electrophysiol, Detroit, MI 48202 USA