ONE-POT GREEN SYNTHESIS OF NOVEL POLYSUBSTITUTED 1,2-DIHYDRONAPHTHO[2,1-b]FURANS

被引：13

作者：

Sadeghpour, Mandieh ^{[1
]}

Olyaei, Abolfazl ^{[2
]}

Lotfiyan, Jamshid ^{[2
]}

Rajabi, Fatemeh ^{[2
]}

机构：

[1] Islamic Azad Univ, Takestan Branch, Dept Chem, Takestan, Iran

[2] PNU, Dept Chem, Tehran, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2015年 / 45卷 / 11期

关键词：

1,2-Dihydronaphtho[2,1-b]furans; 2-aminopyridines; glyoxal; naphthol; SOLVENT; REARRANGEMENT; INHIBITORS; BASES;

D O I：

10.1080/00397911.2015.1017052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and highly efficient one-pot protocol for the synthesis of novel polysubstituted 1,2-dihydronaphtho[2,1-b] furans has been developed by three-component coupling reaction of 2-aminopyridines, naphthols, and glyoxal in the presence of guanidinium chloride as a polyfunctional organocatalyst under solvent-free conditions. The protocol avoids the use of expensive catalysts, toxic solvents, and chromatographic separation and provides a wide range of novel dihydronaphthofurans in good to excellent yields.

引用

页码：1311 / 1320

页数：10

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