Homotopic dynamics of telomeric loops in mammalian chromatids

被引:1
|
作者
Jabbour, M. N. [1 ]
Matioli, G. T. [1 ]
机构
[1] Univ So Calif, Keck Sch Med, Dept Neurol Surg, Los Angeles, CA 90033 USA
关键词
solitonic kinks; telomeres; B-Z DNA; left-right handed "hybrid" coil;
D O I
10.1016/j.jtbi.2007.08.031
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Asymmetric transfer of a solitonic kink between telomeric loops shared by template-replica chromatids is conceptualized in terms of homotopic dynamics. Downscaled to B-Z DNA these ideas lead to interesting possibilities regarding duplication and/or selective activation of genes located at or near DNA "hybrid" chiralities. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:500 / 502
页数:3
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