Sequential isomerization and ring-closing metathesis: masked styryl and vinyloxyaryl groups for the synthesis of benzo-fused heterocycles

被引：71
|
作者：
van Otterlo, WAL [1 ]
Ngidi, EL [1 ]
de Koning, CB [1 ]
机构：
[1] Univ Witwatersrand, Sch Chem, Inst Mol Sci, ZA-2050 Johannesburg, Johannesburg, South Africa
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 34期
关键词：
D O I：
10.1016/S0040-4039(03)01545-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The use of an aryl allyl ether and an arylallyl group as masked vinyl ether and I-propenylphenyl groups for ring-closing metathesis (RCM) leading to the synthesis of benzo-fused heterocycles was demonstrated by using a ruthenium-mediated isomerization followed by a ruthenium-mediated RCM reaction. This resulted in the syntheses of a variety of products including two substituted benzo[1,4]dioxins, a naphtho[2,3-b][1,4]dioxin, a 2H-chromene and a benzo[b]furan. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6483 / 6486
页数：4
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