In-vivo Retinal Imaging by Multi-beam Spectral-domain Optical Coherence Tomography with a Novel Spectrometer

被引:0
|
作者
Suehira, Nobuhito [1 ]
Yoshida, Hirofumi [1 ]
Yuasa, Takashi [1 ]
Sato, Makoto [1 ]
Yamada, Kazuro [1 ]
机构
[1] Canon Inc, Med Imaging Project, Ohta Ku, Tokyo 1468501, Japan
关键词
optical coherence tomography; ophthalmology; multi-beam;
D O I
10.1117/12.873248
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
We have developed a multi-beam spectral-domain optical coherence tomography system with a single line sensor for human retina imaging. Three beams are used and the scan area is a 10-mm square on the fundus. These three beams focus on the fundus at locations 3.1 mm apart from each other to satisfy the ANSI safety standards. The line rate is 70k A-scans/s for each beam, equivalent to a total line rate of 210k A-scans/s for the three beams. The spectrometer has a single line sensor for the three beams, which leads to differences among the three beams such as pixel resolution, roll-off characteristic, and sensitivity. The 3D image is acquired by piecing the images together while calibrating the depth resolution and compensating the roll-off characteristics of each beam. We obtained an image of a healthy human retina.
引用
收藏
页数:8
相关论文
共 50 条
  • [21] Spectral-domain optical coherence tomography and applications for biological imaging
    Li, Peng
    He, Yonghong
    Ma, Hui
    [J]. PROCEEDINGS OF INTERNATIONAL SYMPOSIUM ON BIOPHOTONICS, NANOPHOTONICS AND METAMATERIALS, 2006, : 218 - +
  • [22] Enhanced depth imaging spectral-domain optical coherence tomography
    Spaide, Richard F.
    Koizumi, Hideki
    Pozonni, Maria C.
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 2008, 146 (04) : 496 - 500
  • [23] CHOROIDAL IMAGING USING SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY
    Regatieri, Caio V.
    Branchini, Lauren
    Fujimoto, James G.
    Duker, Jay S.
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2012, 32 (05): : 865 - 876
  • [24] Thickness Mapping of Retinal Layers by Spectral-Domain Optical Coherence Tomography
    Loduca, Ana L.
    Zhang, Chi
    Zelkha, Ruth
    Shahidi, Mahnaz
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 2010, 150 (06) : 849 - 855
  • [25] Spectral-domain optical coherence tomography characteristics of cystic retinal tuft
    Haidong Li
    Lifeng Chen
    Meng’ai Wu
    Bin Zheng
    [J]. BMC Ophthalmology, 22
  • [26] Retinal Surface Prediction in Ophthalmic Spectral-Domain Optical Coherence Tomography
    Wu, Jing
    [J]. 2017 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC), 2017,
  • [27] Spectral-domain optical coherence tomography characteristics of cystic retinal tuft
    Li, Haidong
    Chen, Lifeng
    Wu, Meng'ai
    Zheng, Bin
    [J]. BMC OPHTHALMOLOGY, 2022, 22 (01)
  • [28] Spectral-Domain Optical Coherence Tomography Documentation of Transsynaptic Retinal Degeneration
    Schwartz, Stephen G.
    Pasol, Joshua
    Lam, Byron L.
    Flynn, Harry W., Jr.
    [J]. OPHTHALMIC SURGERY LASERS & IMAGING RETINA, 2016, 47 (08): : 768 - 772
  • [29] Spectral-domain optical coherence tomography imaging of the retinal pigment epithelium in myopic choroidal neovascularization
    Dell'Arti, Laura
    Vezzola, Diego
    Barteselli, Giulio
    Mapelli, Chiara
    Benatti, Eleonora
    Viola, Francesco
    Ratiglia, Roberto
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2014, 55 (13)
  • [30] Quantitative Imaging of Retinal Pigment Epithelial Detachments Using Spectral-Domain Optical Coherence Tomography
    Penha, Fernando M.
    Rosenfeld, Philip J.
    Gregori, Giovanni
    Falcao, Manuel
    Yehoshua, Zohar
    Wang, Fenghua
    Feuer, William J.
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 2012, 153 (03) : 515 - 523