The Optimization of a Lateral Flow Immunoassay for Detection of Aflatoxin B1 in Potable Water Samples

被引：16
|
作者：
Yan, Xiaoxiang [1 ,2 ]
Persaud, Krishna C. [1 ]
机构：
[1] Univ Manchester, Sch Chem Engn & Analyt Sci, Manchester M13 9PL, Lancs, England
[2] Univ Glasgow, Glasgow G12 8QQ, Lanark, Scotland
来源：
IEEE SENSORS JOURNAL | 2019年 / 19卷 / 02期
关键词：
Aflatoxin B-1; biosensor; lateral flow immunoassay; potable water; IMMUNOCHROMATOGRAPHIC ASSAY; LIQUID; SENSITIVITY;
D O I：
10.1109/JSEN.2018.2878449
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Aflatoxin B-1 (AFB(1)) is a highly toxic and carcinogenic metabolite produced by fungi of genus Aspergillus. While AFB(1) contamination in food and crops is well known, little attention has been paid to potable water which is another potential source of AFB(1) contamination that can be ingested by humans. In order to develop a robust, rapidly manufactured sensing device that can monitor the AFB(1) contamination in water, a lateral flow immunostrip based on gold nanoparticles (AuNPs) has been optimized for determination of AFB(1) in potable water samples. A visual detection limit (LOD) of 0.5 ppb was achieved for determination of AFB(1) for the majority of water samples tested. The strip remained functional after being stored at 4 degrees C for 3 months.
引用
收藏
页码：404 / 412
页数：9
相关论文
共 50 条
  • [1] Nanobody-Based Lateral Flow Immunoassay for the Rapid Detection of Aflatoxin B1 in Almond Milk
    Salvador, J. -Pablo
    Vasylieva, Natalia
    Gonzalez-Garcia, Irene
    Jin, Maojun
    Caster, Ryan
    Siegel, Justin B.
    Hammock, Bruce D.
    ACS FOOD SCIENCE & TECHNOLOGY, 2022, 2 (08): : 1276 - 1282
  • [2] A lateral flow assay for simultaneous detection of Deoxynivalenol, Fumonisin B1 and Aflatoxin B1
    Yu, Songcheng
    He, Leiliang
    Yu, Fei
    Liu, Lie
    Qu, Chenling
    Qu, Lingbo
    Liu, Jie
    Wu, Yuming
    Wu, Yongjun
    TOXICON, 2018, 156 : 23 - 27
  • [3] Development of an immunoassay-based lateral flow dipstick for the rapid detection of aflatoxin B1 in pig feed
    Delmulle, BS
    De Saeger, SMDG
    Sibanda, L
    Barna-Vetro, I
    Van Peteghem, CH
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (09) : 3364 - 3368
  • [4] Novel colorimetric immunoassay for the detection of aflatoxin B1
    Garden, SR
    Strachan, NJC
    ANALYTICA CHIMICA ACTA, 2001, 444 (02) : 187 - 191
  • [5] Optimization of a lateral flow immunoassay for the ultrasensitive detection of aflatoxin M1 in milk
    Anfossi, Laura
    Baggiani, Claudio
    Giovannoli, Cristina
    Biagioli, Flavia
    D'Arco, Gilda
    Giraudi, Gianfranco
    ANALYTICA CHIMICA ACTA, 2013, 772 : 75 - 80
  • [6] Nanobody and CuS Nanoflower-Au-Based Lateral Flow Immunoassay Strip to Enhance the Detection of Aflatoxin B1
    Zhao, Yiming
    He, Baoshan
    Li, Danyang
    Gao, Leyan
    Ren, Wenjie
    FOODS, 2024, 13 (12)
  • [7] An Improved Chemiluminescence Immunoassay for the Ultrasensitive Detection of Aflatoxin B1
    Junfeng Li
    Xiangyi Fang
    Yucong Yang
    Xiaoli Cheng
    Peng Tang
    Food Analytical Methods, 2016, 9 : 3080 - 3086
  • [8] An Improved Chemiluminescence Immunoassay for the Ultrasensitive Detection of Aflatoxin B1
    Li, Junfeng
    Fang, Xiangyi
    Yang, Yucong
    Cheng, Xiaoli
    Tang, Peng
    FOOD ANALYTICAL METHODS, 2016, 9 (11) : 3080 - 3086
  • [9] Au@SiO2 SERS nanotags based lateral flow immunoassay for simultaneous detection of aflatoxin B1 and ochratoxin A
    Chen, Ruipeng
    Wang, Hui
    Sun, Chaoqun
    Zhao, Yiguang
    He, Yue
    Nisar, Muhammad Shemyal
    Wei, Wensong
    Kang, Haiqi
    Xie, Xiulan
    Du, Chunmei
    Luo, Qingyao
    Yang, Liang
    Tang, Xiangfang
    Xiong, Benhai
    TALANTA, 2023, 258
  • [10] Colour-encoded lateral flow immunoassay for the simultaneous detection of aflatoxin B1 and type-B fumonisins in a single Test line
    Di Nardo, Fabio
    Alladio, Eugenio
    Baggiani, Claudio
    Cavalera, Simone
    Giovannoli, Cristina
    Spano, Giulia
    Anfossi, Laura
    TALANTA, 2019, 192 : 288 - 294
12345