Metagenomic Analysis of Human Oral Microbiome Composition on the Cloud Platform

被引：0

作者：

Chen, Wen-Pei ^{[1
]}

Tsai, Suh-Jen Jane ^{[1
]}

Liou, Ming-Li ^{[2
,3
]}

Tsai, Chi-Ying ^{[4
]}

Liao, Ki-Hok ^{[5
]}

Chen, Chun-Jung ^{[6
]}

Lin, Yaw-Ling ^{[1
,2
]}

机构：

[1] Providence Univ, Dept Appl Chem, Taichung, Taiwan

[2] Providence Univ, Dept Comp Sci & Informat Engn, Taichung, Taiwan

[3] Yuanpei Univ, Dept Med Lab Sci & Biotechnol, Hsinchu, Taiwan

[4] Chang Gung Mem Hosp, Dept Oral Maxillofacial Surg, Taoyuan, Taiwan

[5] Natl Tsing Hua Univ, Dept Comp Sci, Hsinchu, Taiwan

[6] Taichung Vet Gen Hosp, Dept Med Educ & Res, Taichung, Taiwan

来源：

INTELLIGENT SYSTEMS AND APPLICATIONS (ICS 2014) | 2015年 / 274卷

关键词：

metagenomics; microbiome community; QIIME; Hadoop; MapReduce; SEQUENCES; HEALTH;

D O I：

10.3233/978-1-61499-484-8-2019

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

Metagenomic information provides deeper understanding of the ecological role, metabolism, and evolutionary history of microbes in a given ecosystem by analyzing environmental DNA directly without prior cultivation. In this paper, we propose methods and implement tools and web services to facilitate the bioinformatics analysis of metagenomic data. The open-source metagenomic sequences data analysis softwares and Hadoop Map/Reduce framework were integrated to construct accessible cloud platforms for metagenomic data analysis. The functionality of the platform is examined by composition analysis of human oral microbiome. The metagenomic analysis tools on cloud platforms are accessible by users through the web services with corresponding virtual machine images provided.

引用

页码：2019 / 2029

页数：11

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