Prevalence of New Delhi Metallo Beta-Lactamase (NDM) Producing Gram-Negative Bacteria from Different Tertiary Care Hospitals in Lahore, Pakistan

被引：3
|
作者：
Rashid, Farzana [1 ]
Masood, Rabia [1 ]
Faiz, Mariam [2 ]
机构：
[1] Lahore Coll Women Univ, Dept Zool, Lahore, Pakistan
[2] Inst Nucl Med & Oncol Pakistan, Clin Pathol Labs, Khyber Pakhtunkhwa, Pakistan
来源：
PAKISTAN JOURNAL OF ZOOLOGY | 2020年 / 52卷 / 03期
关键词：
ESBL; Antibiotic resistance; Blac-NDM-1; Pakistan; CARBAPENEMASES; FREQUENCY; THREAT;
D O I：
10.17582/journal.pjz/20190201050207
中图分类号：
Q95 [动物学];
学科分类号：
071002 ;
摘要：
Carbapenem resistance conferred by metallo-beta-lactamase (MBL) has increasingly being reported worldwide among Enterobacteriaceae. In this study, 240 non repetitive gram negative clinical isolates were studied for antimicrobial resistance. Presence of bla NDM was determined by polymerase chain reaction. Among 240 strains, prevalence of MBL in K. pneumoniae, P. aeruginosa, E. coli and Acinetobacter Species was 26%, 52%, 27% and 5% respectively. Prevalence of blaNDM-1 gene was 51% identified in 14 strains of P. aeruginosa, 2 strains of A. Baumanni, 29 strains of E. coli and 18 strains of K. pneumoniae. In conclusion, high prevalence of blaNDM-1 in our strains is a serious concern. A careful use of carbapenems is important to prevent the spread of these organisms.
引用
收藏
页码：1209 / 1212
页数：4
相关论文
共 50 条
  • [21] Prevalence and antibacterial resistance patterns of extended-spectrum beta-lactamase producing Gram-negative bacteria isolated from ocular infections
    Rameshkumar, G.
    Ramakrishnan, R.
    Shivkumar, C.
    Meenakshi, R.
    Anitha, V.
    Reddy, Y. C. Venugopal
    Maneksha, V.
    INDIAN JOURNAL OF OPHTHALMOLOGY, 2016, 64 (04) : 303 - 311
  • [22] Molecular epidemiology of New Delhi metallo-β-lactamase among Gram negative bacteria in a tertiary care hospital of North India
    Singh, S.
    Singh, A.
    Pathak, A.
    Prasad, K. N.
    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2020, 101 : 20 - 20
  • [23] Prevalence of multidrug-resistant and extended-spectrum beta-lactamase producing Gram-negative isolates from clinical samples in a tertiary care hospital of Nepal
    Shilpakar, Aryatara
    Ansari, Mehraj
    Rai, Kul Raj
    Rai, Ganesh
    Rai, Shiba Kumar
    TROPICAL MEDICINE AND HEALTH, 2021, 49 (01)
  • [24] Prevalence of multidrug-resistant and extended-spectrum beta-lactamase producing Gram-negative isolates from clinical samples in a tertiary care hospital of Nepal
    Aryatara Shilpakar
    Mehraj Ansari
    Kul Raj Rai
    Ganesh Rai
    Shiba Kumar Rai
    Tropical Medicine and Health, 49
  • [25] Multidrug resistance and extended-spectrum beta-lactamase producing Gram-negative bacteria from three Referral Hospitals of Amhara region, Ethiopia
    Moges, Feleke
    Gizachew, Mucheye
    Dagnew, Mulat
    Amare, Azanaw
    Sharew, Bekele
    Eshetie, Setegn
    Abebe, Wondwossen
    Million, Yihenew
    Feleke, Tigist
    Tiruneh, Moges
    ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, 2021, 20 (01)
  • [26] Multidrug resistance and extended-spectrum beta-lactamase producing Gram-negative bacteria from three Referral Hospitals of Amhara region, Ethiopia
    Feleke Moges
    Mucheye Gizachew
    Mulat Dagnew
    Azanaw Amare
    Bekele Sharew
    Setegn Eshetie
    Wondwossen Abebe
    Yihenew Million
    Tigist Feleke
    Moges Tiruneh
    Annals of Clinical Microbiology and Antimicrobials, 20
  • [27] Prevalence of extended-spectrum β-lactamase-producing Gram-negative bacteria in septicaemic neonates in a tertiary care hospital
    Jain, A
    Roy, I
    Gupta, MK
    Kumar, M
    Agarwal, SK
    JOURNAL OF MEDICAL MICROBIOLOGY, 2003, 52 (05) : 421 - 425
  • [28] Investigation of the Presence of New Delhi Metallo-Beta-Lactamase-1 (NDM-1) by PCR in Carbapenem-Resistant Gram-Negative Isolates
    Yanik, Keramettin
    Emir, Dilek
    Eroglu, Cafer
    Karadag, Adil
    Guney, Akif Koray
    Gunaydin, Murat
    MIKROBIYOLOJI BULTENI, 2013, 47 (02): : 382 - 384
  • [29] Genetic environment of OXA-2 beta-lactamase producing Gram-negative bacilli from a tertiary referral hospital
    Maurya, Anand Prakash
    Das Talukdar, Anupam
    Dhar , Debadatta
    Chakravarty, Atanu
    Bhattacharjee, Amitabha
    INDIAN JOURNAL OF MEDICAL RESEARCH, 2015, 141 : 368 - 369
  • [30] Prevalence of metallo-beta-lactamase producing Acinetobacter baumannii isolated from intensive care unit in tertiary care hospitals
    Rezaei, A.
    Fazeli, H.
    Halaji, M.
    Moghadampour, M.
    Faghri, J.
    ANNALI DI IGIENE MEDICINA PREVENTIVA E DI COMUNITA, 2018, 30 (04): : 330 - 336
12345